2525 Kerr MG, Rashad MN. Autosomal trisomy in a discordant monozygotic twin. Nature. 1966;212(5063):726-7. http://dx.doi.org/10.1038/212726b0. http://dx.doi.org/10.1038/212726b0...
|
46,XY/47,XY,+C |
F |
9/38 |
46, XY |
L |
- |
2626 Scott JM, Ferguson‐Smith M. Heterokaryotypic monozygotic twins and the acardiac monster. J Obstet Gynaecol Br Commonw. 1973;80(1):52-9. http://dx.doi.org/10.1111/j.1471-0528.1973.tb02131.x. PMid:4735250. http://dx.doi.org/10.1111/j.1471-0528.19...
|
46, XX/47,XX,+ minute chromosomal fragment |
F |
27/4 |
46,XX/47,XX + minute chromosomal fragment |
L |
27/1 |
46,XX |
F |
9 |
2626 Scott JM, Ferguson‐Smith M. Heterokaryotypic monozygotic twins and the acardiac monster. J Obstet Gynaecol Br Commonw. 1973;80(1):52-9. http://dx.doi.org/10.1111/j.1471-0528.1973.tb02131.x. PMid:4735250. http://dx.doi.org/10.1111/j.1471-0528.19...
|
46,XY |
L |
40 |
46,XY |
L |
38 |
47,XY,+G |
F |
50 |
46,XY |
F |
40 |
2727 Rehder H, Geisler M, Kleinbrecht J, Degenhardt K. Monozygotic twins with 47, XXY karyotype and discordant malformations. Teratology. 1978;17:5a.
|
47,XXY |
A |
- |
47,XXY |
A |
- |
F |
F |
2828 Deacon JS, Machin GA, Martin JM, Nicholson S, Nwankwo DC, Wintemute R. Investigation of acephalus. Am J Med Genet. 1980;5(1):85-99. http://dx.doi.org/10.1002/ajmg.1320050112. PMid:7190356. http://dx.doi.org/10.1002/ajmg.132005011...
|
45,X |
F |
20 |
46,XX |
L |
100 |
F |
20 |
2929 Bieber FR, Nance WE, Morton CC, et al. Genetic studies of an acardiac monster: evidence of polar body twinning in man. Science. 1981;213(4509):775-7. http://dx.doi.org/10.1126/science.7196086. PMid:7196086. http://dx.doi.org/10.1126/science.719608...
|
70, XXX+15/see Note 1 |
F |
22/9 |
46, XY |
L |
- |
F |
7/21 |
3030 Van Allen MI, Smith DW, Shepard TH. Twin reversed arterial perfusion (TRAP) sequence: a study of 14 twin pregnancies with acardius. Semin Perinatol. 1983;7(4):285-93. PMid:6658475.
|
45, XX,t(4,21)del(4p) |
U |
- |
46,XX |
U |
- |
3131 Shapiro L, Wilmot P, Duncan P, Davidian M, Fakhry J, Capone A, editors. Holoacardius acephalus: cytogenetic abnormalities as the principle pathogenetic mechanism. In: Proceedings Greenwood Genet Center; 1986; Greenwood. Greenwood, S.C.: The Center; 1986. p. 128.
|
46,XX/47,XX,+11 |
F |
- |
46,XX |
U |
- |
3232 Buehler B, McManus B, Mrocezek E. Acardiac monsters: clinical karyotypic and pathologic features. Teratology. 1986;33:44C.
|
94,XXXXYY |
U |
- |
47,XXY |
U |
- |
3333 Moore CA, Buehler BA, McManus BM, et al. Acephalus‐acardia in twins with aneuploidy. Am J Med Genet Suppl. 1987;28(S3):139-43. http://dx.doi.org/10.1002/ajmg.1320280516. PMid:3130847. http://dx.doi.org/10.1002/ajmg.132028051...
|
Case 1: 94,XXXXYY |
F |
20 |
47,XXY |
L |
50 |
L |
20 |
Case 2: 47,XXY |
F |
20 |
47,XXY |
L |
18 |
3434 Wolf H, MacDonald J, Bradford W. Holoacardius anceps with abnormal karyotype and multicystic renal dysplasia with patent ductus arteriosus in a surviving co-twin. Lab Invest. 1990;62(1): P10-P10.
|
46,X,i(Xp) |
F |
- |
46, XX |
L |
- |
3535 Ginsberg NA, Applebaum M, Rabin SA, et al. Term birth after midtrimester hysterotomy and selective delivery of an acardiac twin. Am J Obstet Gynecol. 1992;167(1):33-7. http://dx.doi.org/10.1016/S0002-9378(11)91620-2. PMid:1442950. http://dx.doi.org/10.1016/S0002-9378(11)...
|
46,XX,inv(10)(p12q25) |
U |
- |
46,XX,inv(10)(p12q25) |
U |
- |
99 Bolaji I, Mortimer G, Meehan F, England S, Greally M. Acardius in a triplet pregnancy: cytogenetic and morphological profile. Acta Genet Med Gemellol (Roma). 1992;41(1):27-32. http://dx.doi.org/10.1017/S0001566000002476. PMid:1488853. http://dx.doi.org/10.1017/S0001566000002...
|
46,XX/hypodiploidy/hyperdiploidy |
L |
18/10/2 |
46, XX (both co-triplets) |
L |
- |
46,XX |
F |
|
3636 Fisk NM, Ware M, Stanier P, Moore G, Bennett P. Molecular genetic etiology of twin reversed arterial perfusion sequence. Am J Obstet Gynecol. 1996;174(3):891-4. http://dx.doi.org/10.1016/S0002-9378(96)70320-4. PMid:8633663. http://dx.doi.org/10.1016/S0002-9378(96)...
|
48,XY,+12,+17 |
A |
14 |
46,XY |
|
|
88 Chaliha C, Schwarzler P, Booker M, Battash M, Ville Y. Case report: Trisomy 2 in an acardiac twin in a triplet in-vitro fertilization pregnancy. Hum Reprod. 1999;14(5):1378-80. http://dx.doi.org/10.1093/humrep/14.5.1378. PMid:10325298. http://dx.doi.org/10.1093/humrep/14.5.13...
|
47,XY,+2 |
F |
- |
46,XY (pump co-triplet) |
U |
|
3737 Blaicher W, Repa C, Schaller A. Acardiac twin pregnancy: associated with trisomy 2: case report. Hum Reprod. 2000;15(2):474-5. http://dx.doi.org/10.1093/humrep/15.2.474. PMid:10655326. http://dx.doi.org/10.1093/humrep/15.2.47...
|
47,XX,+2 |
F |
- |
46,XX |
L |
- |
3838 Mihci E, Velagaleti GV, Ensenauer R, Babovic-Vuksanovic D. The phenotypic spectrum of trisomy 2: report of two new cases. Clin Dysmorphol. 2009;18(4):201-4. http://dx.doi.org/10.1097/MCD.0b013e32832d0639. PMid:19474704. http://dx.doi.org/10.1097/MCD.0b013e3283...
|
47,XX,+2 |
F |
- |
46,XX |
U |
20 |
44 Botto LD, Feldkamp ML, Amar E, et al. Acardia: epidemiologic findings and literature review from the International Clearinghouse for Birth Defects Surveillance and Research. Am J Med Genet C Semin Med Genet. 2011 Nov 15;157C(4):262-73. http://dx.doi.org/10.1002/ajmg.c.30318. PMID: 22002952. http://dx.doi.org/10.1002/ajmg.c.30318...
|
47,XX,+13 |
- |
- |
U |
- |
- |
1010 Kuran J, Niszczota C, Kolesnik A, Dangel JH. P23.15: monochorionic triamniotic triplet pregnancy complicated by twin reversed arterial perfusion (TRAP) sequence. Ultrasound Obstet Gynecol. 2012;40(S1):259. http://dx.doi.org/10.1002/uog.12076. http://dx.doi.org/10.1002/uog.12076...
|
47,XY,+ mar 15 |
- |
- |
U (both co-triplets) |
- |
- |
3939 McHenry A, Morotti R, Hui P. Placenta teratoma or acardiac fetus amorphous: a case study by DNA genotyping. Int J Gynecol Pathol. 2022;41(1):51-8. http://dx.doi.org/10.1097/PGP.0000000000000769. PMid:33770056. http://dx.doi.org/10.1097/PGP.0000000000...
|
Loss of heterozygosity at CSF1PO locus |
Note 2 |
- |
NP |
|
|
4040 Weiss M, Chithiwala Z, Karnezis A, Chien J, Hedriana H, Singh K. P640: Molecular findings of a placental mass in association with neonatal mosaic trisomy 21: Teratoma vs monozygotic acardiac amorphous twin. Genet Med Open. 2023;1(1 Suppl):100696. https://doi.org/10.1016/j.gimo.2023.100696. https://doi.org/10.1016/j.gimo.2023.1006...
|
Trisomy 19 |
Note 3 |
- |
46,XY/47,XY,+21 |
L |
19/3 |
IC |
XX with copy number loss (x1) of 6q11.1 and copy number gain (x3) of 15q25.1 |
F |
- |
NP |
- |
- |