Pan 1997 ( 2525 Pan XR, Li GW, Hu YH, Wang JX, Yang WY, An ZX, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care. 1997;20(4):537-44. ) |
China |
530 |
45.0 |
283 (53.4%) |
25.8 |
IGT |
Dietary and/or exercise individual advice |
Information about diabetes and IGT |
72.0 months |
3 |
Lindahl 1999 ( 2626 Lindahl B, Nilsson TK, Jansson JH, Asplund K, Hallmans G. Improved fibrinolysis by intense lifestyle intervention. A randomized trial in subjects with impaired glucose tolerance. Journal of internal medicine. 1999;246(1):105-12. ) |
Sweden |
186 |
55.5 |
69 (37.1%) |
30.6 |
IGT and obesity |
Dietary and physical activity intervention |
Usual advice |
12.0 months |
4 |
Lindstrom 2003 ( 2727 Lindström J, Eriksson JG, Valle TT, Aunola S, Cepaitis Z, Hakumäki M, et al. Prevention of diabetes mellitus in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study: results from a randomized clinical trial. J Am Soc Nephrol. 2003;14(7 Suppl 2):S108-113. ) |
Finland |
522 |
55.0 |
172 (33.0%) |
31.2 |
IGT and overweight |
Dietary and exercise individual advice |
Information about diet and exercise |
38.0 months |
5 |
Oldroyd 2006 ( 2828 Oldroyd JC, Unwin NC, White M, Mathers JC, Alberti KG. Randomised controlled trial evaluating lifestyle interventions in people with impaired glucose tolerance. Diabetes Res Clin Pract. 2006;72(2):117-27. ) |
UK |
69 |
57.9 |
39 (56.5%) |
NA |
IGT |
Dietary and physical activity advice |
No dietary or physical activity advice |
24.0 months |
3 |
Kawahara 2008 ( 2929 Kawahara T, Takahashi K, Inazu T, Arao T, Kawahara C, Tabata T, et al. Reduced progression to type 2 diabetes from impaired glucose tolerance after a 2-day in-hospital diabetes educational program: the Joetsu Diabetes Prevention Trial. Diabetes Care. 2008;31(10):1949-54. ) |
Japan |
426 |
51.4 |
199 (46.7%) |
24.6 |
IGT |
Diabetes education and support |
Information about diabetes and IGT |
37.0 months |
2 |
Roumen 2008 ( 3030 Roumen C, Corpeleijn E, Feskens EJ, Mensink M, Saris WH, Blaak EE. Impact of 3-year lifestyle intervention on postprandial glucose metabolism: the SLIM study. Diabet Med. 2008;25(5):597-605. ) |
Netherlands |
106 |
56.3 |
58 (54.7%) |
29.4 |
IGT |
Dietary and physical activity advice |
Information about diet and exercise |
36.0 months |
4 |
Yates 2009 ( 3131 Yates T, Davies M, Gorely T, Bull F, Khunti K. Effectiveness of a pragmatic education program designed to promote walking activity in individuals with impaired glucose tolerance: a randomized controlled trial. Diabetes Care. 2009;32(8):1404-10. ) |
UK |
87 |
65.0 |
57 (65.5%) |
29.2 |
IGT |
Structured education program |
Advice leaflet |
12.0 months |
4 |
Bhopal 2014 ( 3232 Bhopal RS, Douglas A, Wallia S, Forbes JF, Lean ME, Gill JM, et al. Effect of a lifestyle intervention on weight change in south Asian individuals in the UK at high risk of type 2 diabetes: a family-cluster randomised controlled trial. Lancet Diabetes Endocrinol. 2014;2(3):218-27. ) |
UK |
171 |
52.5 |
78 (45.5%) |
30.5 |
IGT |
Dietary and physical activity advice |
Standardized written and verbal advice |
36.0 months |
4 |
O’Dea 2015 ( 3333 O’Dea A, Tierney M, McGuire BE, Newell J, Glynn LG, Gibson I, et al. Can the Onset of Type 2 Diabetes Be Delayed by a Group-Based Lifestyle Intervention in Women with Prediabetes following Gestational Diabetes Mellitus (GDM)? Findings from a Randomized Control Mixed Methods Trial. J Diabetes Res. 2015;2015:798460. ) |
Ireland |
50 |
NA |
0 (0.0%) |
35.5 |
IGT |
Multidisciplinary team of nurses, dieticians, and physical activity specialists |
Standard healthcare advice |
12.0 months |
2 |
Van Name 2016 ( 3434 Van Name MA, Camp AW, Magenheimer EA, Li F, Dziura JD, Montosa A, et al. Effective Translation of an Intensive Lifestyle Intervention for Hispanic Women With Prediabetes in a Community Health Center Setting. Diabetes Care. 2016;39(4):525-31. ) |
USA |
122 |
43.4 |
0 (0.0%) |
35.3 |
Prediabetes |
Dietary, behavior, physical activity, and weight loss advice |
Usual care |
12.0 months |
3 |
Nanditha 2016 ( 3535 Nanditha A, Snehalatha C, Ram J, Selvam S, Vijaya L, Shetty SA, et al. Impact of lifestyle intervention in primary prevention of Type 2 diabetes did not differ by baseline age and BMI among Asian-Indian people with impaired glucose tolerance. Diabet Med. 2016;33(12):1700-4. ) |
India |
709 |
46.0 |
NA |
25.9 |
IGT |
Dietary and physical activity advice |
Standard lifestyle modification advice |
24.0 months |
4 |
Gokulakrishnan 2017 ( 3636 Gokulakrishnan K, Ranjani H, Weber MB, Pandey GK, Anjana RM, Balasubramanyam M, et al. Effect of lifestyle improvement program on the biomarkers of adiposity, inflammation and gut hormones in overweight/obese Asian Indians with prediabetes. Acta diabetologica. 2017;54(9):843-52. ) |
India |
150 |
44.5 |
91 (60.6%) |
28.0 |
Prediabetes and overweight/obese |
Dietary and physical activity advice |
Standard lifestyle advice |
12.0 months |
2 |
Salas-Salvado 2019 ( 3737 Salas-Salvadó J, Díaz-López A, Ruiz-Canela M, Basora J, Fitó M, Corella D, et al. Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial. Diabetes Care. 2019;42(5):777-88. ) |
Spain |
248 |
65.0 |
NA |
32.5 |
Prediabetes and overweight/obese |
Dietary, behavior, physical activity advice |
Educational sessions on an ad libitum med-diet |
12.0 months |
4 |