NORMATIVE VALUES FOR EGJ-CI FOR A WATER-PERFUSED ESOPHAGEAL MANOMETRY SYSTEM

Valores de normalidade para o EGJ-CI de um sistema de manometria esofágica de perfusão de água

Dear Editor,

The Chicago Classification has been the leading guideline for esophageal motility disorders evaluation and classification since the advent of high-resolution manometry. Esophagogastric junction (EGJ) barrier function was neglected until the most current update of the classification when a technical review on the topic was recently released¹. In this publication, the Contractility Integral of the Esophagogastric Junction (EJG-CI) was deemed “currently the best validated metric of EGJ contractile vigor and should be adopted”.

Each manometry system has different reference values depending on its operating mechanism. This is mainly visible in water perfusion systems, where the response of the sensors is slower, given the latency of the response time to the passage of water through the sensors. We have published normative values for a 24-channel water-perfused system (Multiplex, Alacer Biomédica, São Paulo, Brazil)². Mean basal respiratory pressure was used then as a parameter for measuring the competence of the lower esophageal sphincter (LES) as EJG-CI was not widely used. We present here the reference values for EGJ-CI for the same population of healthy individuals previously studied after reanalysis of the tests (Table 1).

TABLE 1
Normative values for Contractility Integral of the Esophagogastric Junction (EJG-CI) for a water-perfuse esophageal manometry system.

Mean	Median	Standard Deviation	IQ 25	IQ 75	Maximum	Minimum	Percentile 5	Percentile 95
40.96	38.50	26.64	21.60	55.22	128.30	0.60	14.17	84.39

REFERENCES

• ¹
  Kahrilas PJ, Mittal RK, Bor S, Kohn GP, Lenglinger J, Mittal SK, et al. Chicago Classification update (v4.0): Technical review of high-resolution manometry metrics for EGJ barrier function. Neurogastroenterol Motil. 2021;33:e14113. doi: 10.1111/nmo.14113.
  » https://doi.org/10.1111/nmo.14113.
• ²
  Silva RMBD, Herbella FAM, Gualberto D. Normative values for a new water-perfused high. Arq Gastroenterol. 2018;(Suppl 1):30-34

• Disclosure of funding: no funding received

Publication Dates

• Publication in this collection
  06 July 2022
• Date of issue
  Apr-Jun 2022

History

• Received
  06 Dec 2021
• Accepted
  17 Jan 2022