Acessibilidade / Reportar erro

FIRST ISOLATION OF EQUINE HERPESVIRUS TYPE 1 FROM A HORSE WITH NEUROLOGICAL DISEASE IN BRAZIL

PRIMEIRO ISOLAMENTO NO BRASIL DE HERPESVIRUS EQÜINO TIPO 1 EM UM CAVALO COM DOENÇA NEUROLÓGICA

ABSTRACT

This report describes the first Brazilian equine herpesvirus type 1 (EHV-1) isolation from a single fatal equine herpes myeloencephalopathy case in a mare. The isolation of EHV-1 was confirmed from the first passage of cerebrospinal fluid (CSF) sample in Vero cells by PCR and virus neutralization assay. As virus isolation from CSF is unlikely to be successful, as has been shown in several case reports, this circumstantial evidence suggests that the neurological disease was caused by particularly neurovirulent strain of EHV-1.

KEY WORDS
Equine herpesvirus type 1; EHV-1; myeloencephalopathy; cerebrospinal fluid; virus isolation

Instituto Biológico Av. Conselheiro Rodrigues Alves, 1252 - Vila Mariana - São Paulo - SP, 04014-002 - São Paulo - SP - Brazil
E-mail: arquivos@biologico.sp.gov.br