INTRODUCTION: Localized amyloidosis is a rare disease characterized by extracellular deposition of proteins that can occur in various regions of the body. The larynx is the most common site of disease in head and neck. OBJECTIVE: We present a literature review and the case of a patient with extensive amyloidosis in the upper aerodigestive tract, whose resection was performed in four steps. CASE REPORT: SMS, 28 years, 4 months ago dysphonia. Complementary exams showed large lesions in supraglottic that was removed in four stages by microlaryngoscopy. FINAL COMMENTS: microlaryngoscopy tiered approach was effective and safe resection of lesions in amyloidosis large.
amyloidosis; larynx; microsurgery