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Mielite transversa como manifestação clínica inicial de linfoma não Hodgkin disseminado e mielopatia vacuolar associada ao HIV: relato de caso

Transverse myelitis as initial symptom of disseminated non-Hodgkin lymphoma and HIV-associated vacuolar myelopathy: case report

Resumos

Linfomas não Hodgkin de alto grau são comumente relatados em pacientes com a síndrome da imunodeficiência adquirida (AIDS). Comprometendo com grande freqüência o sistema nervoso central, particularmente as leptomeninges e os hemisférios cerebrais. O acometimento epidural é pouco freqüente, variando de 3,5% a 8,3% de acordo com os registros da literatura. Os autores relatam o caso de um paciente de 27 anos de idade com AIDS, cuja manifestação clínica inicial da doença linfomatosa disseminada foi a mielite transversa associada à mielopatia vacuolar. Destaca-se a importância do diagnóstico diferencial precoce das mielopatias na AIDS, em virtude da alta malignidade da neoplasia e da evolução extremamente rápida nesses pacientes.

mielite transversa; linfoma não Hodgkin; mielopatia vacuolar; AIDS


Non-Hodgkin lymphoma is frequently seen in AIDS patients usually affecting the central nervous system (CNS), especially the leptomeninges and the cerebral hemispheres. The epidural involvement is rarely described, ranging from 3.5% to 8.3% among the CNS sites. The authors present a case of disseminated non Hodgkin lymphoma associated to vacuolar myelopathy in a 27 years-old male patient with AIDS emphasizing the importance of this differential diagnosis in the myelopathies of AIDS.

acute transverse myelitis; non-Hodgkin lymphoma; vacuolar myelopathy; AIDS


Mielite transversa como manifestação clínica inicial de linfoma não Hodgkin disseminado e mielopatia vacuolar associada ao HIV: relato de caso

Transverse myelitis as initial symptom of disseminated non-Hodgkin lymphoma and HIV-associated vacuolar myelopathy: case report

Leandro P. de MouraI; Marco T. A. SilvestreII; Fátima R. N. AraújoII; Marcius K. N. BurgarelliII; Aércio S. BorgesII; Fernando A. VinhalIII; Ademir RochaIV; Cesar N. RaffinV; Marcelo S. FerreiraVI

INeurologista

IIInfectoIogista

IIIResidente de Clínica Médica

IVProfessor Titular de Anatomia Patológica, Departamento de Patologia

VProfessor Titular de Neurologia - Departamento de Cirurgia

VIProfessor Titular de Infectologia, Departamento de Clínica Médica

RESUMO

Linfomas não Hodgkin de alto grau são comumente relatados em pacientes com a síndrome da imunodeficiência adquirida (AIDS). Comprometendo com grande freqüência o sistema nervoso central, particularmente as leptomeninges e os hemisférios cerebrais. O acometimento epidural é pouco freqüente, variando de 3,5% a 8,3% de acordo com os registros da literatura. Os autores relatam o caso de um paciente de 27 anos de idade com AIDS, cuja manifestação clínica inicial da doença linfomatosa disseminada foi a mielite transversa associada à mielopatia vacuolar. Destaca-se a importância do diagnóstico diferencial precoce das mielopatias na AIDS, em virtude da alta malignidade da neoplasia e da evolução extremamente rápida nesses pacientes.

Palavras-chave: mielite transversa, linfoma não Hodgkin, mielopatia vacuolar, AIDS.

ABSTRACT

Non-Hodgkin lymphoma is frequently seen in AIDS patients usually affecting the central nervous system (CNS), especially the leptomeninges and the cerebral hemispheres. The epidural involvement is rarely described, ranging from 3.5% to 8.3% among the CNS sites. The authors present a case of disseminated non Hodgkin lymphoma associated to vacuolar myelopathy in a 27 years-old male patient with AIDS emphasizing the importance of this differential diagnosis in the myelopathies of AIDS.

Key words: acute transverse myelitis, non-Hodgkin lymphoma, vacuolar myelopathy, AIDS.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Aceite: 30-janeiro-1996.

Faculdade de Medicina da Universidade Federal de Uberlândia, Minas Gerais

Dr. Leandro Pajuaba de Moura - Rua Johen Carneiro 825 - 38400-031 Uberlândia MG - Brasil Fax 034 218 2246.

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Datas de Publicação

  • Publicação nesta coleção
    06 Dez 2010
  • Data do Fascículo
    Jun 1996
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