Lymphomatous meningoencephalitis in a patient with HAMVTSP

Gomes, Irenio; Nascimento, Marco Heleno Cunha; Moreno-Carvalho, Otávio Augusto; Melo, Ailton

doi:10.1590/S0004-282X1995000100019

Abstracts

A case of lymphomatous meningoencephalitis in a 23 year old Brazilian patient with HTLV-I/II associated myelopathy is reported. The patient was admitted to the hospital with a clinical picture of decreased consciousness level, stiffness of the neck and previous diagnosis of myeloneuropathy. CSF examination showed lymphocytosis with blastic cells and antibodies against HTLV-I/II.

HTLV-I; meningoencephalitis; lymphoma

É descrito o caso de um paciente de 23 anos, com diagnóstico prévio de mielorradiculopatia que desenvolveu diminuição gradual do nível de consciência, rigidez de nuca e cefaléia. O exame do LCR mostrou linfocitose com presença de células blásticas, hiperproteinorraquia e anticorpos para HTLV-I/II.

HTLV-I; meningo-encefalite; linfoma

Lymphomatous meningoencephalitis in a patient with HAMVTSP

Meningo-encefalite linfomatosa em um paciente com HAMVTSP

Irenio Gomes^I; Marco Heleno Cunha Nascimento^II; Otávio Augusto Moreno-Carvalho^III; Ailton Melo^IV

^INeurologista da Unidade de Neurojinfectologia da Universidade Federal da Bahia (UFBA)

^IIMonitor de Departamento de Neuropsiquiatria, UFBA

^IIIResponsável pelo Laboratório de Liquorologia do Hospital Santo Amaro, Salvador

^IVResponsáveI pela Unidade de Neuroinfectologia da UFBA, Pesquisador do CNPq

SUMMARY

A case of lymphomatous meningoencephalitis in a 23 year old Brazilian patient with HTLV-I/II associated myelopathy is reported. The patient was admitted to the hospital with a clinical picture of decreased consciousness level, stiffness of the neck and previous diagnosis of myeloneuropathy. CSF examination showed lymphocytosis with blastic cells and antibodies against HTLV-I/II.

Key words:HTLV-I, meningoencephalitis, lymphoma.

RESUMO

É descrito o caso de um paciente de 23 anos, com diagnóstico prévio de mielorradiculopatia que desenvolveu diminuição gradual do nível de consciência, rigidez de nuca e cefaléia. O exame do LCR mostrou linfocitose com presença de células blásticas, hiperproteinorraquia e anticorpos para HTLV-I/II.

Palavras-chave: HTLV-I, meningo-encefalite, linfoma.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Acknowledgements

We are indebted to Professor Aristides Chetto de Queiroz for his kind assistance.

Aceite: 28-setembro-1994.

Dr. Ailton Melo - Departamento de Neuropsiquiatria, Faculdade de Medicina, UFBA - Av. Reitor Miguel Calmon s/n - 40110-100 Salvador BA - Brasil.

1. Arango C, Concha M, Zaninovic V, Corral R, Biojo J, Borrero I, Rodgers-Johnson P, Mora C, Garruto RM, Gibbs CI Jr. Epidemiology of tropical spastic paraparesis in Colombia and associated HTLV-I infection. Ann Neurol 1988, 23(Suppl): S161-S16S.
2. Bittencourt AL, Fernnandes DJ, Sampaio C, Moreira ED Jr, Ribeiro TT, Harrington W Jr. HTLV-I associated cutaneous T-cell lyphoma: report of a case with atypical clinical presentation. Mem Inst Osw Cruz (in press).
3. Cortes E, Detels R, Aboulafia D, Li XL, Maudgil T, Alan M, Bonecker C, Gonzaga A, Oyafuso L, Tondo M. HIV-1, HIV-2 and HTLV-1 infection in high risk groups in Brazil. N Engl J Med 1989, 220:953-958.
4. Gessain A, Gout O. Chronic myelopathy associated with human T-lymphotropic virus type I (HTLV-I). Ann Intern Med 1992, 117:933-946.
5. Iwasaki Y. Human T cell leukemia virus type-I infection and chronic myelopathy. Brain Pathol 1993, 3:1-10.
6. Melo A, Moura L, Rios S, Machado M, Costa G. Magnetic resonance imaging in HTLV-I associated myelopathy. Arq Neuropsiquiatr 1993, 51:329-332.
7. Melo A, Gomes I, Mattos K. Mielopatia por HTLV-I: uma doença sistêmica. Arq Neuropsiquiatr 1994, 52:443-444.
8. Melo A, Gomes I, Mattos K. Mielopatia por HTLV-I/II em Salvador/Bahia. Arq Neuropsiquiatr 1994, 52:320-325.
9. Melo A, Freitas V, Bittencourt AL, Fernandes DJ, Mattos K, Gomes I. Adult T-cell leukemia-lymphoma in a patient with HTLV-I/II associated myelopathy. J Neurol 1994, 241: S6.
10. Mattos K, Queiroz C, Peçanha-Martins AC, Publio L, Vinhas V, Melo A. Lymphocyte alveolitis in HAM/ TSP patients. Arq Neuropsiquiatr 1993, 51:134-136.
11. Moreira ED Jr, Ribeiro TT, Swanson P, Sampaio C, Melo A, Brites C, Badaró R, Toedter G, Lee H, Harrington W Jr. Seroepidemiology of human T-cell lymphotropic virus type I/II in Northeastern Brazil. J AIDS 1993, 959-963.
12. Osame M. Igata A, Matsumoto M, Kohka M, Usuku K, Izumo S. HTLV-I associated myelopathy: treatment trials, retrospective survey and clinical and laboratory findings. Hematol Rev 1990, 3: 271-274.
13. Said G, Goulon-Goeau C, Lacroix C, Feve A, Descamps H, Fouchard M. Inflammatory lesions of peripheral nerve in a patient with human T lymphotropic virus type I-associated myelopathy. Ann Neurol 1988, 24:275-277.

Publication Dates

Publication in this collection
19 Jan 2011
Date of issue
Mar 1995

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Arango C, Concha M, Zaninovic V, Corral R, Biojo J, Borrero I, Rodgers-Johnson P, Mora C, Garruto RM, Gibbs CI Jr. Epidemiology of tropical spastic paraparesis in Colombia and associated HTLV-I infection. Ann Neurol 1988, 23(Suppl): S161-S16S.

[2] 2. Bittencourt AL, Fernnandes DJ, Sampaio C, Moreira ED Jr, Ribeiro TT, Harrington W Jr. HTLV-I associated cutaneous T-cell lyphoma: report of a case with atypical clinical presentation. Mem Inst Osw Cruz (in press).

[3] 3. Cortes E, Detels R, Aboulafia D, Li XL, Maudgil T, Alan M, Bonecker C, Gonzaga A, Oyafuso L, Tondo M. HIV-1, HIV-2 and HTLV-1 infection in high risk groups in Brazil. N Engl J Med 1989, 220:953-958.

[4] 4. Gessain A, Gout O. Chronic myelopathy associated with human T-lymphotropic virus type I (HTLV-I). Ann Intern Med 1992, 117:933-946.

[5] 5. Iwasaki Y. Human T cell leukemia virus type-I infection and chronic myelopathy. Brain Pathol 1993, 3:1-10.

[6] 6. Melo A, Moura L, Rios S, Machado M, Costa G. Magnetic resonance imaging in HTLV-I associated myelopathy. Arq Neuropsiquiatr 1993, 51:329-332.

[7] 7. Melo A, Gomes I, Mattos K. Mielopatia por HTLV-I: uma doença sistêmica. Arq Neuropsiquiatr 1994, 52:443-444.

[8] 8. Melo A, Gomes I, Mattos K. Mielopatia por HTLV-I/II em Salvador/Bahia. Arq Neuropsiquiatr 1994, 52:320-325.

[9] 9. Melo A, Freitas V, Bittencourt AL, Fernandes DJ, Mattos K, Gomes I. Adult T-cell leukemia-lymphoma in a patient with HTLV-I/II associated myelopathy. J Neurol 1994, 241: S6.

[10] 10. Mattos K, Queiroz C, Peçanha-Martins AC, Publio L, Vinhas V, Melo A. Lymphocyte alveolitis in HAM/ TSP patients. Arq Neuropsiquiatr 1993, 51:134-136.

[11] 11. Moreira ED Jr, Ribeiro TT, Swanson P, Sampaio C, Melo A, Brites C, Badaró R, Toedter G, Lee H, Harrington W Jr. Seroepidemiology of human T-cell lymphotropic virus type I/II in Northeastern Brazil. J AIDS 1993, 959-963.

[12] 12. Osame M. Igata A, Matsumoto M, Kohka M, Usuku K, Izumo S. HTLV-I associated myelopathy: treatment trials, retrospective survey and clinical and laboratory findings. Hematol Rev 1990, 3: 271-274.

[13] 13. Said G, Goulon-Goeau C, Lacroix C, Feve A, Descamps H, Fouchard M. Inflammatory lesions of peripheral nerve in a patient with human T lymphotropic virus type I-associated myelopathy. Ann Neurol 1988, 24:275-277.