Drug interactions in epilepsy

Interações de medicamentos na epilepsia

Drug interactions in epilepsy

Interações de medicamentos na epilepsia

Emilio Perucca, M.D

Research Fellow and Clinical Assistant, Institute of Neurology, The National Hospital, Queen Square, London WC1N 3BG, England

SUMMARY AND CONCLUSIONS

Interactions with antiepileptic drugs are common and may have important clinical consequences. The physician should always consider carefully the need for and the implications of adding a new drug to any therapeutic regime and should be prepared to think about the possibility of an interaction whenever an unusual response is seen. Serum drug levels can be an invaluable tool in the recognition and the management of most types of interactions, but in no case can they be a substitute for careful observations and evaluation of the patient's symptoms and physical findings.

RESUMO E CONCLUSOES

Interações com fármacos anticonvulsivantes são comuns e podem ter consequências clínicas importantes. O médico deve sempre cuidadosamente considerar a necessidade e as implicações da adição de uma nova droga a qualquer regime terapêutico, e deve estar preparado para pensar na possibilidade de uma interação sempre que uma resposta anormal for notada. Níveis séricos podem ser de valor inestimável no diagnóstico e na conduta da maior parte das interações, mas nunca substituem a cuidadosa observação e avaliação clínica.

Full text available only in PDF format.

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Clinical Pharmacology Unit - Institute of Neurology - National Hospital - Queen Square - London WC1N 3BG. Enoland.

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Publication Dates

• Publication in this collection
  23 Aug 2012
• Date of issue
  Dec 1980