Present concepts on the immunobiology of cysticercosis are reviwed considering the experience on cysticercosis of the central nervous system. For this puspose data related to cysticercus biology, to histopathology of the disease, to biologic aspects evidenced through laboratory investigations and radiology are discussed and evaluated. The lack of experimental studies is stressed and the importance of studies on immunoproteins are pointed out. Informations resulting from these studies might explain many of the doubts that are patent when the concepts on the pathogeny of the disease are considered.