Guillan-Barré syndrome in children

THESES

Guillan-Barré syndrome in children (Abstract)^*. Dissertation. São Paulo, 2003.

Vanessa Van Der Linden^**

SUBJECT: The aim of the study was to trace the epidemiologic, clinical, laboratory and evolution profile of Guillain-Barré syndrome (GBS) casuistics at the Instituto da Criança of Hospital das Clínicas of Faculty of Medicine of the University of Sao Paulo (FMUSP) between 1989 and 2000.

METHOD: Patients were studied retrospectively and casuistic was defined by consulting Instituto da Criança data base and data was collect through a structured protocol.

RESULTS: From the 61 patients that fulfilled the selection criteria, aged between 7 months to 13 years old, no sexual or seasonal variation was observed. A clinical event prior to neurological symptoms (with a medium gap of time of 20.7 days) was observed in 62.3%, 55% had cranial nerve disturbs, 27.9% dysautonomic symptoms, and 27.9% respiratory dysfunction. The progression time variated from 2-40 days, Plato from 0-28 days and recuperation from 30-480 days; 94% had a complete clinical recuperation. ENMG in 20 patients disclosed a demyelinating pattern in 15, exclusively motor axonal pattern in 4 and a mixed pattern in 1 patient.

CONCLUSION: The results obtained did not differ from those in literature but it was observed that boys and older children had a recuperation time longer. It was not possible to ascertain ENMG with clinics and evolution due to the reduced number of patients submitted to this evaluation.

Key Words: Guillain-Barré syndrome, acute flacid palsy, children, epidemiology, prognosis.

*

Síndrome de Guillain-Barré na infância (Resumo). Dissertação de Mestrado, Universidade de São Paulo, USP (Área: Pediatria). Orientadora: Maria Joaquina Marques-Dias.

**

Address: Rua Conselheiro Portela 243 / 1702 - 52020-000 Refice PE, Brasil.

Publication Dates

• Publication in this collection
  28 Apr 2004
• Date of issue
  Mar 2004