Abstract in Portuguese:

O AA. apresentam um caso anátomo-clínico de mielite neuro-ópti-ca aguda. A moléstia evoluiu em 35 dias, tendo o quadro medular se completado no 31° dia. Nos três dias que precederam a morte, estabeleceram-se rapidamente as síndromes óptica (amauróse progressiva) e encefálica, esta com fenômenos bulbares graves. O doente faleceu por broncopneumonia de aspiração. A autópsia evidenciou edema encéfalo-medular e fenômenos inflamatorios de tipo não supurado nas vias ópticas, bulbo e medula; nesta, predominavam no entumescimento cervical, onde ocasionaram verdadeira secção transversa. O quadro anátomo-patológico mostrou particular eletividade para a substância branca dos cordões lateral e posterior da medula. A reação inflamatória era constituída por células linfocitóides, predominantemente, em tôdos os pontos atingidos.

Abstract in English:

The authors present a clinicopathological case of acute neuro-optic myelitis. The course of the disease was of 35 days and the spinal symptomatology was established only at the end of 31 days. In the three days before the death, the optic (progressive amaurosis) ami encephalic syndromes have rapidly developed, showing severe medullary signs. The patient died of aspiration bronchopneumonia. The necroscopic examination evidenced cerebrospinal edema and inflamma tory phenomena of non-suppurating type in the optic pahtways, medulla and spinal cord; in the latter, they predominanted in the intumescencia cervicalis, where they actually caused a transverse section. The pathological picture exhibited particular electivity for the white substance of the lateral and posterior funiculi of the spinal cord. The inflammatory reaction was preponderantly constituted by lymphocytoid cells.

Abstract in English:

The antibacterial action of penicillin in the presence as well as in the absence of pus, and the innocuousness of its therapeutic concentra-tions in relation to tissues in general, tend to further stimulate the generalized practice of its use in prophylactic and in curative treatment of local infections. This study was undertaken to evaluate the influence of penicillin on nerve regeneration, both under asseptic conditions and in the presence of contamination. This preliminary note refers only to partial results observed in the aseptic material. In these animals, whether treated or not with penicillin, nerve regeneration developed in a like manner, and along the usual general lines.

Abstract in Portuguese:

E' relatado o caso de um indivíduo jovem, de 32 anos, preto, obeso, com artério e arteriolosclerose, desacompanhadas de hipertensão. O paciente teve hemiplegia direita, amaurose esquerda por arteriosclerose dos vasos retiníanos, e bloqueio aurículo-ventricular completo. A biópsia do músculo peitoral mostrou arteriolosclerose. Provas renais normais. Os autores comentam a possibilidade de se ter estabelecido a arteriolosclerose na ausência de hipertensão.

Abstract in English:

The authors report a case of a negro and obese young man, 32 years old, with arterio and arteriolosclerosis, without arterial hypertension. The patient had right hemiparesis, left amaurosis due to arteriosclerosis of the retineal vessels, and total auriculoventricular block. The biopsy of the pectoralis muscle showed arteriolosclerosis. The renal tests were normal. The authors comment the possibility that arteriolosclerosis can appear in the absence of arterial hypertension.

Abstract in Portuguese:

E' relatado um caso de meningite pneumocócica pós-otite e mastoidite, tratado com sucesso pela penicilina associada à sulfapiridina. Tanto o composto sulfonamídico como a penicilina isoladamente não tiveram efeito terapêutico satisfatório. A evolução da meningite é estudada por exames diários do liqüido cefalorraquidiano.

Abstract in English:

The author reports a case of pneumococcic meningitis following otitis and mastoiditis, successfully treated by penicillin associated with sulfapy-ridine. Neither the sulfonamidic compound nor the penicillin, separately, have been effective. The course of the meningitis was studied by means of daily examinations of the cerebrospinal fluid.