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Effectiveness of antiemetics in control of antineoplastic chemotherapy-induced emesis at home

Objective

Evaluating if antiemetics are effective in the prevention or treatment at home, of chemotherapy-induced emesis.

Methods

In total, were included 42 women with breast cancer in moderately emetogenic chemotherapy, using dexamethasone/ondansetron before each cycle. The frequency of nausea and vomiting was obtained by applying the instrument in the pre-chemotherapy period, and 24h, 48h, 72h and 96h after chemotherapy. The use of antiemetics was considered in accordance with adherence to medical prescription.

Results

All patients (n = 42, 100%) reported emesis at some point. Only five cases (11.9%) were anticipatory. In the first 24 hours (acute emesis), 38 (90.5%)ayed), emesis was reported by all despite the regular use (n = 20, 47.6%) or not (n = 22, 52.4%) of antiemetics (ondansetron, dexamethasone and metoclopramide/or dimenhydrinate).

Conclusion

Antiemetics were not effective in the prevention or treatment at home, of chemotherapy-induced emesis.

Vomiting/chemically induced; Chemotherapy; Antinoeplastics agents/adverse effects; Antiemetics; Oncology nursing; Residential treatment


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