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Mechanical ventilation and acute kidney injury in patients in the intensive care unit

Objective

To verify the impact of mechanical ventilation use in patients admitted to the intensive care unit and the incidence of acute kidney injury.

Methods

A prospective, quantitative cohort study of 27 patients receiving mechanical ventilatory support while hospitalized in the intensive care unit of a public hospital.

Results

The majority (55.6%) of patients were classified according to the kidney injury stages listed in the Risk, Injury, Failure, Loss, End-Stage (RIFLE) classification. Of these patients, 45.8% received mechanical ventilation with between 5 and 10 cmH2O positive end-expiratory pressure and progressed to acute kidney injury. The Acute Physiology and Chronic Health Disease Classification System II (APACHE II) was significantly associated with renal dysfunction (p = 0.046).

Conclusion

The use of invasive mechanical ventilator support with positive end-expiratory pressure in critically ill patients in intensive care units can impair renal function.

Acute kidney injury; Respiration, artificial; Nursing assessment; Intensive care units


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