Flavonoids |
↓ Mortality from heart disease |
Mink et al. (2007)MINK, P. J.; SCRAFFORD, C. G.; BARRAJ, L. M.; HARNACK, L.; HONG, C. P.; NETTLETON, J. A.; JACOBS JUNIOR, D. R. Flavonoid intake and cardiovascular disease mortality: a prospective study in post-menopausal women. The American Journal of Clinical Nutrition, v. 85, n. 3, p. 895-909, 2007. PMid:17344514.
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Red wine (procyanidins) |
↑ FMD response and coronary microcirculation |
Hozumi et al. (2006)HOZUMI, T.; SUGIOKA, K.; SHIMADA, K.; KIM, S. H.; KUO, M. Y.; MIYAKE, Y.; FUJIMOTO, K.; OTSUKA, R.; WATANABE, H.; HOSODA, K.; YOSHUKAWA, J.; HOMMA, S. Beneficial effect of short term intake of red wine polyphenols on coronary microcirculation in patients with coronary artery disease. Heart and Vessels, v. 92, n. 5, p. 681-682, 2006. http://dx.doi.org/10.1136/hrt.2004.059204. http://dx.doi.org/10.1136/hrt.2004.05920...
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Cacao flavonols (procyanidins) |
↑ FMD response |
Balzer et al. (2008)BALZER, J.; RASSAF, T.; HEISS, C.; KLEINBONGARD, P.; LAUER, T.; MERX, M.; HEUSSEN, N.; GROSS, H. B.; KEEN, C. L.; SCHROETER, H.; KELM, M. Sustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trial. The Journal of Nutrition, v. 137, n. 22, p. 1401-1407, 2008. PMid:18510961.
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↑ Endothelial function, patients with coronary disease |
Heiss et al. (2010)HEISS, C.; JAHN, S.; TAYLOR, M.; REAL, W. M.; ANGELI, F. S.; WONG, M. L.; AMABILE, N.; PRASAD, M.; RASSAF, T.; OTTAVIANI, J. I.; MIHARDJA, S.; KEEN, C. L.; SPRINGER, M. L.; BOYLE, A.; GROSSMAN, W.; GLANTZ, S. A.; SCHROETER, H.; YEGHIAZARIANS, Y. Improvement of endothelial function with dictary flavonois associated with mobilization of circulating angiogenic cells in patients with coronary artery disease. Journal of the American College of Cardiology, v. 56, n. 3, p. 218-224, 2010. PMid:20620742. http://dx.doi.org/10.1016/j.jacc.2010.03.039. http://dx.doi.org/10.1016/j.jacc.2010.03...
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Apple (Epicatechin) |
↑ Increases vasodilation |
Castilla et al. (2006)CASTILLA, P.; ECHARRI, R.; DÁVALOS, A.; CERRATO, F.; ORTEGA, H.; TERUEL, J. L.; LUCAS, M. F.; GÓMEZ-CORONADO, D.; ORTUÑO, J.; LASUNCIÓN, M. A. Concentrated red grape juice exerts antioxidante, hypolipidemic and inflammatory effects in both hemodialysis patients and healthly subjects. The American Journal of Clinical Nutrition, v. 84, p. 252-263, 2006. PMid:16825703.
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↓ Decreases plasma lipid |
Fermented milk (peptides; VPP, IPP) |
↓ Lowers blood pressure |
Pripp (2008)PRIPP, A. H. Effect of peptides derived from food proteins on blood pressure: a meta-analysis of randomised trials. Food & Nutrition Research, v. 52, p. 103402, 2008.
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Xu et al. (2008)XU, J. Y.; QIN, L. Q.; WANG, P. Y.; LI, W.; CHANG, C. Effect of milk tripeptides on blood pressure: a meta-analysis of randomised controlled trials. Nutrition Journal, v. 24, n. 10, p. 933-940, 2008. PMid:18562172. http://dx.doi.org/10.1016/j.nut.2008.04.004. http://dx.doi.org/10.1016/j.nut.2008.04....
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Whole grains |
↓ Reduces CVD risk mechanisms: reduces inflammatory conditions, improves insulin response, improves vascular function and blood pressure, modifies lipid profile, facilitates weight control, pre-biotic e antioxidant function in the GIT |
Seal and Brownlee (2010)SEAL, C. J.; BROWNLEE, I. A. Whole grains and health, evidence from observational and intervention studies. Cereal Chemistry, v. 87, n. 2, p. 167-174, 2010. http://dx.doi.org/10.1094/CCHEM-87-2-0167. http://dx.doi.org/10.1094/CCHEM-87-2-016...
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Aqueous tomato concentrate (FruitflowTM) |
↓ Reduces platelet aggregation (prevents blood clots) |
O’Kennedy et al. (2006)O’KENNEDY, N.; CROSBIE, L.; VAN LIESHOUT, M.; BROOM, J. I.; WEBB, D. J.; DUTTAROY, A. K. Effects of antiplateler components of tomato extract on plateler function in vitro and ex vivo a time-course cannulation study in healthy humans. The American Journal of Clinical Nutrition, v. 84, n. 3, p. 570-5709, 2006. PMid:16960171.
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