Bacteria
|
|
|
|
|
|
|
Yersinia Pseudotuberculosis Q66CJ |
SmF |
62.7 U mg−1
|
0.017 |
8.0 |
60 |
5454 Pokrovskaya MV, Aleksandrova SS, Pokrovsky VS, et al. Cloning, expression and characterization of the recombinant Yersinia pseudotuberculosis L-asparaginase. Protein Expr Purif. 2012;82(1):150-154, http://dx.doi.org/10.1016/j.pep.2011.12.005. http://dx.doi.org/10.1016/j.pep.2011.12....
|
Bacillus aryabhattai ITBHU02 |
SmF |
680.5 U mg−1
|
0.257 |
8.5 |
40 |
5555 Singh Y, Gundampati RK, Jagannadham MV, Srivastava SK. Extracellular L-asparaginase from a protease-deficient bacillus aryabhattai ITBHU02: purification, biochemical characterization, and evaluation of antineoplastic activity in vitro. Appl Biochem Biotechnol. 2013;171(7):1759-1774, http://dx.doi.org/10.1007/s12010-013-0455-0. http://dx.doi.org/10.1007/s12010-013-045...
|
Pseudomonas fluorescens
|
SmF |
168.4 U mL−1
|
110 |
8 |
37 |
5656 Prema P, Devi MN, Alagumanikumaran N. Production of tumor inhibitory L-asparaginase by wild and mutant strains of Pseudomonas fluorescens. Int J Adv Res J. 2013;1(4):163-171.
,
5757 Kishore V, Nishita KP, Manonmani HK. Cloning, expression and characterization of L-asparaginase from Pseudomonas fluorescens for large scale production in E. coli BL21. 3 Biotech. 2015;5(6):975-981, http://dx.doi.org/10.1007/s13205-015-0300-y. http://dx.doi.org/10.1007/s13205-015-030...
|
Bacillus licheniformis RAM-8 |
SmF |
697.1 U mg−1
|
0.014 |
6-10 |
40 |
5858 Mahajan RV, Kumar V, Rajendran V, Saran S, Ghosh PC, Saxena RK. Purification and characterization of a novel and robust L-asparaginase having low-glutaminase activity from Bacillus licheniformis: in vitro evaluation of anti-cancerous properties, trackman PC. PLoS ONE. 2014;9(6):e99037, http://dx.doi.org/10.1371/journal.pone.0099037. http://dx.doi.org/10.1371/journal.pone.0...
|
Nocardiopsis alba NIOT-VKMA08 |
SmF |
158.1 U mL−1
|
0.127 |
8 |
37 |
5959 Meena B, Anburajan L, Dheenan PS, et al. Novel glutaminase free L-asparaginase from Nocardiopsis alba NIOT-VKMA08: production, optimization, functional and molecular characterization. Bioprocess Biosyst Eng. 2015;38(2):373-388, http://dx.doi.org/10.1007/s00449-014-1277-3. http://dx.doi.org/10.1007/s00449-014-127...
,
6060 Meena B, Anburajan L, Vinithkumar NV, et al. Molecular expression of L-asparaginase gene from Nocardiopsis alba NIOT-VKMA08 in Escherichia coli: a prospective recombinant enzyme for leukaemia chemotherapy. Gene. 2016, http://dx.doi.org/10.1016/j.gene.2016.05.003. http://dx.doi.org/10.1016/j.gene.2016.05...
|
Streptomyces noursei MTCC 10469 |
SmF |
0.803 U mg−1
|
25 µM |
7.5 |
50 |
6161 Dharmaraj S. Study of L-asparaginase production by Streptomyces noursei MTCC 10469, isolated from marine sponge Callyspongia diffusa. Iran J Biotechnol. 2011;9(2):102-108.
|
Pectobacterium carotovorum MTCC 1428 |
SmF |
35.24 U mg−1
|
657 µM |
8-10 |
40 |
4444 Kumar S, Dasu VV, Pakshirajan K. Localization and production of novel L-asparaginase from Pectobacterium carotovorum MTCC 1428. Process Biochem. 2010;45(2):223-229, http://dx.doi.org/10.1016/j.procbio.2009.09.011. http://dx.doi.org/10.1016/j.procbio.2009...
|
Streptomyces parvulus KUA106 |
SmF |
146 U mL−1
|
25 µM |
7.5 |
50 |
6262 Usha R, Mala KK, Venil CK, Palaniswamy M. Screening of actinomycetes from mangrove ecosystem for L-asparaginase activity and optimization by response surface methodology. Polish J Microbiol/Pol Tow Mikrobiol=Polish Soc Microbiol. 2011;60(3):213-221. http://www.ncbi.nlm.nih.gov/pubmed/22184928 Accessed 18.08.16. http://www.ncbi.nlm.nih.gov/pubmed/22184...
|
Bacillus subtilis hswx88 |
SmF |
23.8 U mL−1
|
430 µM |
7.5 |
40 |
6363 Jia M, Xu M, He B, Rao Z. Cloning, expression, and characterization of L-asparaginase from a newly isolated Bacillus subtilis B11-06. J Agric Food Chem. 2013;61(39):9428-9434, http://dx.doi.org/10.1021/jf402636w. http://dx.doi.org/10.1021/jf402636w...
|
Streptomyces ginsengisoli
|
SmF |
3.32 U mL−1
|
25 µM |
7.5 |
30 |
3131 Deshpande N, Choubey P, Agashe M. Studies on optimization of growth parameters for L-asparaginase production by streptomyces ginsengisoli. Sci World J. 2014;2014:1-6, http://dx.doi.org/10.1155/2014/895167. http://dx.doi.org/10.1155/2014/895167...
|
Streptomyces thermoluteus NBRC 14270 |
SmF |
68.09 U mg−1
|
1830 |
8-9 |
63.6 |
6464 Hatanaka T, Usuki H, Arima J, et al. Extracellular production and characterization of two Streptomyces L-asparaginases. Appl Biochem Biotechnol. 2011;163(7):836-844, http://dx.doi.org/10.1007/s12010-010-9087-9. http://dx.doi.org/10.1007/s12010-010-908...
|
Photobacterium sp. J15 |
- |
20 U mg−1
|
760 |
7.0 |
25 |
6565 Yaacob MA, Hasan WANW, Ali MSM, et al. Characterisation and molecular dynamic simulations of J15 asparaginase from Photobacterium sp. strain J15. Acta Biochim Pol. 2014;61(4):745-752. http://www.ncbi.nlm.nih.gov/pubmed/25337608 Accessed 18.08.16. http://www.ncbi.nlm.nih.gov/pubmed/25337...
|
Pyrococcus furiosus
|
SmF |
550 U mg−1
|
12,000 |
9.0 |
85 |
6666 Bansal S, Gnaneswari D, Mishra P, Kundu B. Structural stability and functional analysis of L-asparaginase from Pyrococcus furiosus. Biochemistry. 2010;75(3):375-381, http://dx.doi.org/10.1134/S0006297910030144. http://dx.doi.org/10.1134/S0006297910030...
|
Bacillus licheniformis MTCC 429 |
SmF |
597.8 U mg−1
|
0.420 |
8 |
37 |
6767 Sudhir AP, Agarwaal VV, Dave BR, Patel DH, Subramanian RB. Enhanced catalysis of L-asparaginase from Bacillus licheniformis by a rational redesign. Enzyme Microb Technol. 2016;86:1-6, http://dx.doi.org/10.1016/j.enzmictec.2015.11.010. http://dx.doi.org/10.1016/j.enzmictec.20...
|
|
|
|
|
|
|
|
Fungi
|
|
|
|
|
|
|
Talaromyces pinophilus
|
SmF |
145 U mg−1
|
6.4 |
8 |
28 |
6868 Krishnapura PR, Belur PD. Partial purification and characterization of L-asparaginase from an endophytic Talaromyces pinophilus isolated from the rhizomes of Curcuma amada. J Mol Catal B Enzym. 2016;124:83-91, http://dx.doi.org/10.1016/j.molcatb.2015.12.007. http://dx.doi.org/10.1016/j.molcatb.2015...
|
Trichoderma viride
|
SmF |
78.2 U mg−1
|
0.003 |
6.5 |
37 |
6969 Lincoln L, Niyonzima FN, More SS. Purification and properties of a fungal L-asparaginase from trichoderma viride pers: sf grey. J Microbiol Biotechnol food Sci. 2015, http://dx.doi.org/10.15414/JMBFS.2014.4.4.310-316. http://dx.doi.org/10.15414/JMBFS.2014.4....
|
Aspergillus aculeatus
|
SmF |
207 U mg−1
|
12.5 |
9.0 |
30 |
7070 Dange VU, Peshwe SA. Production, purification andcharacterizationof fungal L-asparaginase. Bionano Front. 2011;4:162-167.
|
Cladosporium sp. |
SSF |
83.3 U mg−1
|
100 |
6.3 |
30 |
7171 Mohan Kumar NS, Manonmani HK. Purification, characterization and kinetic properties of extracellular L-asparaginase produced by Cladosporium sp. World J Microbiol Biotechnol. 2013;29(4):577-587, http://dx.doi.org/10.1007/s11274-012-1213-0. http://dx.doi.org/10.1007/s11274-012-121...
|
Rhizomucor miehei
|
SmF |
1985 U mg−1
|
- |
7.0 |
45 |
2626 Huang L, Liu Y, Sun Y, Yan Q, Jiang Z. Biochemical characterization of a novel L-asparaginase with low glutaminase activity from Rhizomucor miehei and its application in food safety and leukemia treatment. Appl Environ Microbiol. 2014;80(5):1561-1569, http://dx.doi.org/10.1128/AEM.03523-13. http://dx.doi.org/10.1128/AEM.03523-13...
|
Penicillium digitatum
|
SmF |
833.15 U mg−1
|
10 |
7.0 |
30 |
7272 Shrivastava A, Khan AA, Shrivastav A, Jain SK, Singhal PK. Kinetic studies of L-asparaginase from Penicillium digitatum. Prep Biochem Biotechnol. 2012;42(6):574-581, http://dx.doi.org/10.1080/10826068.2012.672943. http://dx.doi.org/10.1080/10826068.2012....
|
Penicillium sp. |
SmF |
13.97 U mg−1 |
4000 |
7.0 |
37 |
7373 Patro KR, Gupta N. Extraction, purification and characterization of L-asparaginase from Penicillium sp. by submerged fermentation. Int J Biotechnol Mol Biol Res. 2012;3(3):30-34, http://dx.doi.org/10.5897/IJBMBR11.066. http://dx.doi.org/10.5897/IJBMBR11.066...
|
Penicillium brevicompactum NRC 829 |
SmF |
574.24 U mg−1
|
1050 |
8.0 |
37 |
7474 Elshafei AM, Hassan MM, Abouzeid MA-E, Mahmoud DA, Elghonemy DH. Purification, characterization and antitumoractivity of L-asparaginase from Penicillium brevicompactum NRC 829. Br Microbiol Res J. 2012;2(3):158-174.
|
Mucor hiemalis
|
SmF |
69.43 U mg−1
|
4.3 |
7 |
37 |
7575 Thakur M, Lincoln L, Niyonzima FN, More SS. Isolation, purification and characterization of fungal extracellular L-asparaginase from Mucor hiemalis. J Biocatal Biotransform. 2013;2(2), http://dx.doi.org/10.4172/2324-9099.1000108. http://dx.doi.org/10.4172/2324-9099.1000...
|