Highlights
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Performance of screening instruments for obstructive sleep apnea.
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Obstructive sleep apnea screening in different age groups.
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The STOP-Bang questionnaire has high sensitivity for screening OSA.
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ROC curve and area under the curve of three sleep disorder screening instruments.
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Age has no significant influence on the screening for obstructive sleep apnea.
Abstract
Objective
To evaluate the performance of the Berlin Questionnaire, the STOP-Bang Questionnaire, and the Epworth Sleepiness Scale in screening for the disease in adults of different age groups by comparing them with polysomnography.
Methods
Cross-sectional study with prospective patient allocation, in which individuals underwent a medical interview, completion of the three screening instruments, and polysomnography. Individuals were categorized into three age groups: 18-39, 40-59, and ≥60 years. The results of the screening instruments were compared to the diagnostic criteria of the International Classification of Sleep Disorders—third edition. Performance was assessed using 2 × 2 contingency tables, estimating sensitivity, specificity, predictive value, likelihood ratio, and accuracy. Receiver Operating Characteristic curves were also constructed and the area under the curve was estimated for each instrument by age group.
Results
We obtained a sample with 321 individuals suitable for analysis. The mean age was 50 years, with a predominance of females (56%). The prevalence of the disease in the overall sample was 79%, more prevalent in males in any age group and more frequent in the middle age group. The analyzes revealed that STOP-Bang performed better, both for the overall sample and for all age groups, followed by Berlin Questionnaire and Epworth Sleepiness Scale.
Conclusion
In an outpatient setting with individuals with characteristics similar to those in this study, it seems sensible to choose the STOP-Bang as a screening tool for the disease, regardless of age group.
Level of evidence according the guide for authors: level 2.
Keywords
Sleep apnea; Age groups; Surveys and questionnaires; Diagnostic techniques and procedures; Polysomnography