Abstract
Objective:
We aimed to reveal whether there is nasal involvement by examining the Nasal Mucociliary Clearance (NMC) and the relationship between this activity and disease severity in Rheumatoid Arthritis (RA) patients.
Methods:
In this prospective study, NMC time, disease activity (Disease Activity Score 28) and blood parameters of RA patients (n = 87) were investigated and compared with the healthy control group (n = 50). In addition, the relationship between DAS 28 and NMC was investigated.
Results:
The mean NMC of the RA group was 9.51 ± 3.54 min, the mean NMC of the control group was 8.69 ± 2.85 min, and there was no significant difference between the two groups. There was no correlation between NMC and disease duration, and DAS 28. The mean NMC of the RA patients with Anti Cyclic Citrulled Peptide (Anti-CCP) positive was significantly higher than the negative ones.
Conclusion:
Although there was no significant difference in NMC values between the RA and control group, the NMC of the Anti-CCP positive patients was higher.
Level of evidence:
Level 2.
KEYWORDS
Rheumatoid arthritis; Nasal mucociliary clearance; Disease activity score
HIGHLIGHTS
Nasal involvement has not been fully addressed in Rheumatoid Arthritis (RA).
Nasal Mucociliary Clearance (NMC) time of RA patients was within normal limits and was similar to the control group.
Anti-cyclic citrated peptide (Anti-CCP) positivity may affect NMC time in RA patients.