| WO9965915A1 (Bousquet, Castro, Saint-Germain, op cit) |
15/06/1998 |
Sanofi- Synthelabo |
Clopidogrel bisulfate form II |
| WO03051362A2 (Lifshitz-Liron
et al, 2003LIFSHITZ-LIRON, R.; KOVALEVSKI-ISHAL, E.; WIZEL, S.; AVHAR-MAYDAN, S.;
LIDOR-HADAS, R. Polymorphs of clopidogrel hydrogenesulfate. WO. Pat.03051362A2,
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18/12/2001 |
Teva Pharmaceuticals |
Clopidogrel bisulfate forms III, IV, V and VI; amorphous clopidogrel
bisulfate. |
| WO03066637A1 (Kótay Nagy et al., 2003) |
06/02/2002 |
Egys Gyogyszervegyeszet Gyar. |
Clopidogrel hydrochloride, forms I and II |
| PL355514A1 (Piechaczek et
al., 2004PIECHACZEK, J.; SERAFIN, J.; MARUSZAK, W.; BALICKI, R.; SZELEJEWSKI, W.;
CYBULSKI, M.; MACIEJEWSKI, G.; WYSOCZYNSKA, M.; GLICE, M.; KORCZAK, K. Amorphous form
of clopidogrel bisulphate, method of its manufacture and pharmaceutical compounds
containing it. PL. Pat.355514, 2004., op cit) |
14/08/2002 |
Instytut Farmaceutyczny. |
No data retrieved |
| WO2004026879A1 (Rao, Kankan, op cit) |
19/09/2002 |
Cipla Ltd. |
Amorphous clopidogrel bisulfate; complex with dissolution
enhancer |
| WO2004052966A1 (Narasa et
al., 2004NARASA, R.A.; NAGI, R.B.; RATNAKAR, K.R.; RAJI, R.R. A novel polymorph
of clopidogrel hydrogen sulfate. WO. Pat.2004052966, 2004.) |
09/12/2002 |
Heterodrugs Ltd. |
Clopidogrel bisulfate form III |
| WO2004081015A1 (Parthasaradhi
et al., 2004PARTHASARADHI, R.B.; RATHNAKAR, R.K.; RAJI, R.R.; MURALIDHARA, R.D.
Amorphous clopidogrel hydrogen sulfate.WO. Pat.2004081015, 2004.) |
10/03/2003 |
Heterodrugs Ltd. |
Amorphous clopidogrel bisulfate |
| WO2004081016A1 (Lohray et
al, 2004LOHRAY, B.B.; LOHRAY, V.B.; PANDEY, B.; DAVE, M.G. Polymorphs and
amorphous form of (S)-(+)-clopidogrel bisulfate. WO. Pat.2004081016,
2004.) |
12/03/2003 |
Cadila Healthcare Ltd. |
Amorphous clopidogrel bisulfate and mixtures with forms I and
II |
| WO2005026174A1 (Arul, et
al, 2007ARUL, R.; RAWAT, A.S.; GADAKAR, M.; RAO, R.; PISE, A.; GRAY, J. Novel
crystalline polymorphs of clopidogrel. WO. Pat.2005026174, 2005.) |
11/09/2003 |
Generics Limited |
Clopidogrel hydrobromide forms 1, 2 and 3 |
| CZ295386B6 (Hajicek, Pihera,
Stepnkova, 2005bHAJICEK, J.; PIHERA, P.; STEPANKOVA, H. Clopidogrel hidrobromide in
crystalline form II and process for its preparation. CZ. Pat.295386,
2005b.) |
13/01/2004 |
Zentiva |
Clopidogrel hydrobromide form II |
| WO2005068471A1 (Hajicek, Pihera,
Stepnkova, 2005aHAJICEK, J.; PIHERA, P.; STEPANKOVA, H. New crystalline forms of
clopidogrel hydrobromide and methods of their preparation. WO. Pat.2005068471,
2005a.) |
13/01/2004 |
Zentiva |
Clopidogrel hydrobromide forms I, II and III |
| WO2005080890A1 (Weber, Levis, Ly, op cit) |
24/02/2004 |
Siegfried Generics Int. Ag. |
Clopidogrel hydrobromide forms A, B, C, D, E and F. Clopidogrel
napsylate forms A and B |
| WO2005117866A1 (Kaznakov, Veverkova,
Veverka, 2005KAZNAKOV, V.; VEVERKOVA, E.; VEVERKA, M. Amorphous clopidogrel
hydrochloride and its antithrombotic use. WO. Pat.2005117866, 2005.) |
01/06/2004 |
Ivax Corporation |
Clopidogrel hydrochloride amorphous form |
| WO2006034451A2 (Finkelstein,
Arohrime, Tessler, 2006FINKELSTEIN, N.; ARONHIME, J.; TESSLER, L. Crystalline clopidogrel
hydrobromide and processes for preparation thereof. WO. Pat.2006034451,
2006.) |
21/09/2004 |
Teva Pharmaceuticals |
Clopidogrel hydrobromide Forms I, II, III, IV, V, VI, VII, VIII, IX
and X |
| EP1674468A1 (Jetti, Gersser,
2006JETTI, R.K.; GRIESSER, U. Polymorphs of clopidogrel hydrobromide. EP.
Pat.1674468, 2006.) |
21/12/2004 |
Ratiopharm GMBH. |
Clopidogrel hydrobromide forms A, B, C, D and E; Clopidogrel
hydrobromide monohydrate forms Hy-1 and Hy-2 |
| WO2005103058A1 (Lorimer, Ng,
2005aLORIMER, K.R.; NG, A.T.F. Clopidogrel salt and polymorphic forms
thereof. WO. Pat.2005103058. 2005a.) |
20/04/04 |
Sanofi Aventis Co. |
Clopidogrel hydrobromide forms B, C and D |
| WO2005103059A1 (Lorimer, Ng,
2005bLORIMER, K.R.; NG, A.T.F. Polymorphic forms of methyl (+) - (s) -alpha-
(2-chlorophenyl) -6, 7-dihydrothieno `3,2-c!pyridine-584h) acetate hydrobromide,
clopidrogel hydrobromide. WO. Pat.2005103059, 2005b.) |
20/04/04 |
Sanofi Aventis Co. |
Several polymorphs and hydrates of clopidogrel
1,5-naphtalenedisulfonate |
| WO200702096A2 (Gangakhedkar,
2007GANGAKHEDKAR- KAR, K. Novel polymorphic forms of clopidogrel
hydrochloride. WO. Pat.2007029096, 2007.) |
05/09/2005 |
Ranbaxy Lab. Ltd. |
Clopidogrel hydrochloride form III |
| WO2008034912A2 (Simonic et
al., 2008SIMONIC, I.; BENKIC, P.; ZUPET, R.; SMRKOLJ, M.; STUKELJ, M. Process for
the synthesis of clopidogrel and new forms of pharmaceutically acceptable salts
thereof. WO. Pat.2008034912, 2008.) |
22/09/2006 |
Krka Tovarna Zdravil DD novo. |
Several clopidogrel camphor-10-sulfonate forms; Clopidogrel
bisulfate form I; Clopidogrel hydrochloride form |
| EP1903046A1 (Majka et
al., 2008MAJKA, Z.; SAWICKI, A.W.; TRZEPALKA, A.; ADAMKIEWICZ, M. New clopidogrel
salt and its crystalline forms. EP. Pat.1903046, 2008.) |
25/09/2006 |
Adamed SP ZOO. |
Clopidogrel 5- sulfosalicylic acid forms I and II |
| WO2008046792A1 (Majka, Sawicki,
Trizepal, 2008MAJKA, Z.; SAWICKI, A.W.; TRZEPALKA, A. Crystalline form of the racemic
methyl-α-(2-chlorphenyl)-2-(6,7-dihydrothieno[3,2-c]pyridine-5(4h)) acetate, method
for the production and use thereof. WO. Pat.2008046792, 2008.) |
17/10/2006 |
Adamed SP ZOO. |
Racemic clopidogrel polymorph |
| WO2008108742A2 (Veverka et al., 2008) |
08/03/2007 |
Krka Tovarna Zdravil DD novo. |
Clopidogrel hydrobromide forms α, β, and γ; Amorphous
clopidogrel hydrobromide |
| KR20090004268A (Ho et al., 2009a) |
06/07/2007 |
SK Chemicals CO Ltd. |
No data retrieved |
| KR20090004269A (Ho et al., 2009b) |
06/07/2007 |
SK Chemicals CO Ltd |
No data retrieved |
