Abstract:

This study aimed to analyze the 100 most-cited articles on intraoral squamous cell carcinoma and its risk factors. A literature search was conducted on November 12, 2020 using the Web of Science database. Bibliometric data were collected after study selection. Bibliometric maps were generated using VOSviewer software. Articles were ranked based on the number of citations, ranging from 108 to 1513 per study. Eleven studies presented at least 400 citations. Articles were published between 1950 and 2017 and were mostly case-control studies (n = 39) and narrative reviews (n = 29). The author and institution in most articles were S. Franceschi (n = 10) and the International Agency for Research on Cancer (n = 10), respectively. The most prominent countries were the United States (n = 35), the United Kingdom (n = 16), and France (n = 9). Among the 100 most-cited articles, only one article was from Brazil, and the authors were affiliated with the Ludwig Institute for Cancer Research. Bibliometric maps showed strong associations between the terms alcohol, smoked/smokeless tobacco, and human papillomavirus. Emerging terms, such as areca nut and betel quid, were cited in recent articles. In conclusion, alcohol, tobacco, and human papillomavirus were the most prominent risk factors. Case-control design was the most common study design, and the majority of studies were conducted in the United States by the International Agency for Research on Cancer.

Keywords:
Bibliometrics; Mouth Neoplasms; Alcohol Drinking; Areca; Epidemiologic Factors; Tobacco Products; Research Design

Rank	Reference	Citations	Citation density^* * Citation density = mean number of citations per year.
1	Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncology. 2009;45(4-5):309-16. https://doi.org/10.1016/j.oraloncology.2008.06.002.	1,513	137.55
2	Herrero R, Castellsague X, Pawlita M, Lissowska J, Kee F, Balaram P, et al. Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. Journal of the National Cancer Institute. 2003;95(23):1772-83. https://doi.org/10.1093/jnci/djg/107.	837	49.24
3	Neville BW, Day TA. Oral cancer and precancerous lesions. CA-A Cancer Journal For Clinicians. 2002;52(4):195-215. https://doi.org/10.3322/canjclin.52.4.195.	647	35.94
4	Bhaskaran K, Douglas I, Forbes H, dos-Santos-Silva I, Leon DA, Smeeth L. Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults. Lancet. 2014;384(9945):755-65. https://doi.org/10.1016/S0140-6736(14)60892-8.	636	106.00
5	Mork J, Lie AK, Glattre E, Clark S, Hallmans G, Jellum E, et al. Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. New England Journal of Medicine. 2001;344(15):1125-31. https://doi.org/10.1056/NEJM200104123441503.	625	32.89
6	Hashibe M, Brennan P, Benhamou S, Castellsague X, Chu C, Curado MP, et al. Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Journal of the National Cancer Institute. 2007;99(10):777-89. https://doi.org/10.1093/jnci/djk179.	576	44.31
7	Hashibe M, Brennan P, Chuang SC, Boccia S, Castellsague X, Chen C, et al. Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiology Biomarkers & Prevention. 2009;18(2):541-50. https://doi.org/10.1158/1055-9965.EPI-08-0347.	556	50.55
8	Ko YC, Huang YL, Lee CH, Chen MJ, Lin LM, Tsai CC. Betel quid chewing, cigarette-smoking and alcohol-consumption related to oral-cancer in Taiwan. Journal of Oral Pathology & Medicine. 1995;24(10):450-3. https://doi.org/10.1111/j.1600-0714.1995.tb01132.x.	516	20.64
9	Winn DM, Blot WJ, Shy CM, Pickle LW, Toledo A, Fraumeni JF. Snuff dipping and oral-cancer among women in the southern United States. New England Journal of Medicine. 1981;304(13):745-9. https://doi.org/10.1056/NEJM198103263041301.	474	12.15
10	Rothman K, Keller A. Effect of joint exposure to alcohol and tobacco on risk of cancer of mouth and pharynx. Journal of Chronic Diseases. 1972;25(12):711-6. https://doi.org/10.1016/0021-9681(72)90006-9.	413	8.60
11	Schwartz SM, Daling JR, Doody DR, Wipf GC, Carter JJ, Madeleine MM, et al. Oral cancer risk in relation to sexual history and evidence of human papillomavirus infection. Journal of the National Cancer Institute. 1998;90(21):1626-36. https://doi.org/10.1093/jnci/90.21.1626.	410	18.64
12	Boffetta P, Hecht S, Gray N, Gupta P, Straif K. Smokeless tobacco and cancer. Lancet Oncology. 2008;9(7):667-75. https://doi.org/10.1016/S1470-2045(08)70173-6.	337	28.08
13	Miller CS, Johnstone BM. Human papillomavirus as a risk factor for oral squamous cell carcinoma: a meta-analysis, 1982-1997. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology. 2001;91(6):622-35. https://doi.org/10.1067/moe.2001.115392.	295	15.53
14	Silverman S. Demographics and occurrence of oral and pharyngeal cancers - the outcomes, the trends, the challenge. Journal of the American Dental Association. 2001;132:7S-11S. https://doi.org/10.14219/jada.archive.2001.0382.	291	15.32
15	Llewellyn CD, Johnson NW, Warnakulasuriya S. Risk factors for squamous cell carcinoma of the oral cavity in young people - a comprehensive literature review. Oral Oncology. 2001;37(5):401-18. https://doi.org/10.1016/S1368-8375(00)00135-4.	290	15.26
16	Mashberg A, Boffetta P, Winkelman R, Garfinkel L. Tobacco smoking, alcohol-drinking, and cancer of the oral cavity and oropharynx among United-States veterans. Cancer. 1993;72(4):1369-75. https://doi.org/10.1002/1097-0142(19930815)72:4<1369::AID-CNCR2820720436>3.0.CO;2-L.	281	10.41
17	La Vecchia C, Tavani A, Franceschi S, Levi F, Corrao G, Negri E. Epidemiology and prevention of oral cancer. Oral Oncology. 1997;33(5):302-12.	278	12.09
18	Syrjanen S. Human papillomavirus (HPV) in head and neck cancer. Journal of Clinical Virology. 2005;32:S59-S66. https://doi.org/10.1016/j.jcv.2004.11.017.	275	18.33
19	Graham S, Dayal H, Rohrer T, Swanson M, Sultz H, Shedd D, et al. Dentition, diet, tobacco, and alcohol in epidemiology of oral cancer. Journal of the National Cancer Institute. 1977;59(6):1611-8. https://doi.org/10.1093/jnci/59.6.1611.	264	6.14
20	Franco EL, Kowalski LP, Oliveira BV, Curado MP, Pereira RN, Silva ME, et al. Risk-factors for oral-cancer in Brazil - a case-control study. International Journal of Cancer. 1989;43(6):992-1000. https://doi.org/10.1002/ijc.2910430607.	258	8.32
21	Jeng JH, Chang MC, Hahn LJ. Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives. Oral Oncology. 2001;37(6):477-92. https://doi.org/10.1016/S1368-8375(01)00003-3.	257	13.53
22	Nair U, Bartsch H, Nair J. Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: a review of agents and causative mechanisms. Mutagenesis. 2004;19(4):251-62. https://doi.org/10.1093/mutage/geh036.	247	15.44
23	Gupta PC, Ray CS. Smokeless tobacco and health in India and South Asia. Respirology. 2003;8(4):419-31. https://doi.org/10.1046/j.1440-1843.2003.00507.x.	244	14.35
24	Scully C, Bagan J. Oral squamous cell carcinoma overview. Oral Oncology. 2009;45(4-5):301-8. https://doi.org/10.1016/j.oraloncology.2009.01.004.	242	22.00
25	Ragin CCR, Modugno F, Gollin SM. The epidemiology and risk factors of head and neck cancer: a focus on human papillomavirus. Journal of Dental Research. 2007;86(2):104-14. https://doi.org/10.1177/154405910708600202.	235	18.08
26	Hobbs CGL, Sterne JAC, Bailey M, Heyderman RS, Birchall MA, Thomas SJ. Human papillomavirus and head and neck cancer: a systematic review and meta-analysis. Clinical Otolaryngology. 2006;31(4):259-66. https://doi.org/10.1111/j.1749-4486.2006.01246.x.	232	16.57
27	Vigneswaran N, Williams MD. Epidemiologic trends in head and neck cancer and AIDS in diagnosis. Oral and Maxillofacial Surgery Clinics of North America. 2014;26(2):123-41. https://doi.org/10.1016/j.coms.2014.01.001.	227	37.83
28	Kademani D. Oral cancer. Mayo Clinic Proceedings. 2007;82(7):878-87. https://doi.org/10.4065/82.7.878.	214	16.46
29	Chen YJ, Chang JTC, Liao CT, Wang HM, Yen TC, Chiu CC, et al. Head and neck cancer in the betel quid chewing area: recent advances in molecular carcinogenesis. Cancer Science. 2008;99(8):1507-14. https://doi.org/10.1111/j.1349-7006.2008.00863.x.	209	17.42
30	Znaor A, Brennan P, Gajalakshmi V, Mathew A, Shanta V, Varghese C, et al. Independent and combined effects of tobacco smoking, chewing and alcohol drinking on the risk of oral, pharyngeal and esophageal cancers in indian men. International Journal of Cancer. 2003;105(5):681-6. https://doi.org/10.1002/ijc.11114.	206	12.12
31	Critchley JA, Unal B. Health effects associated with smokeless tobacco: a systematic review. Thorax. 2003;58(5):435-43. https://doi.org/10.1136/thorax.58.5.435.	202	11.88
32	Heck JE, Berthiller J, Vaccarella S, Winn DM, Smith E, Shangina O, et al. Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. International Journal of Epidemiology. 2010;39(1):166-81. https://doi.org/10.1093/ije/dyp350.	201	20.10
33	Homann N, Tillonen J, Meurman JH, Rintamaki H, Lindqvist C, Rautio M, et al. Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer. Carcinogenesis. 2000;21(4):663-8. https://doi.org/10.1093/carcin/21.4.663.	199	9.95
34	Pavia M, Pileggi C, Nobile CGA, Angelillo IF. Association between fruit and vegetable consumption and oral cancer: a meta-analysis of observational studies. American Journal of Clinical Nutrition. 2006;83(5):1126-34.	195	13.93
35	Scully C, Field JK, Tanzawa H. Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. carcinogen metabolism, dna repair and cell cycle control. Oral Oncology. 2000;36(3):256-63. https://doi.org/10.1016/S1368-8375(00)00007-5.	187	9.35
36	Chung FL, Schwartz J, Herzog CR, Yang YM. Tea and cancer prevention: studies in animals and humans. Journal of Nutrition. 2003;133(10):3268S-74S.	186	10.94
37	Kreimer AR, Johansson M, Waterboer T, Kaaks R, Chang-Claude J, Drogen D, et al. Evaluation of human papillomavirus antibodies and risk of subsequent head and neck cancer. Journal of Clinical Oncology. 2013;31(21):2708-15. https://doi.org/10.1200/JCO.2012.47.2738.	185	26.43
38	Balaram P, Sridhar H, Rajkumar T, Vaccarella S, Herrero R, Nandakumar A, et al. Oral cancer in southern india: the influence of smoking, drinking, paan-chewing and oral hygiene. International Journal of Cancer. 2002;98(3):440-5. https://doi.org/10.1002/ijc.10200.	184	10.22
39	Rivera C. Essentials of oral cancer. International Journal of Clinical and Experimental Pathology. 2015;8(9):11884-94.	183	36.60
40	Rao SVK, Mejia G, Roberts-Thomson K, Logan R. Epidemiology of oral cancer in Asia in the past decade- an update (2000-2012). Asian Pacific Journal of Cancer Prevention. 2013;14(10):5567-77. https://doi.org/10.7314/APJCP.2013.14.10.5567.	181	25.86
41	Syrjanen S, Lodi G, von Bultzingslowen I, Aliko A, Arduino P, Campisi G, et al. Human papillomaviruses in oral carcinoma and oral potentially malignant disorders: a systematic review. Oral Diseases. 2011;17:58-72. https://doi.org/10.1111/j.1601-0825.2011.01792.x.	179	19.89
42	Petti S, Scully C. Polyphenols, oral health and disease: a review. Journal of Dentistry. 2009;37(6):413-23. https://doi.org/10.1016/j.jdent.2009.02.003.	179	16.27
43	Warnakulasuriya S, Dietrich T, Bornstein MM, Peidro EC, Preshaw PM, Walter C, et al. Oral health risks of tobacco use and effects of cessation. International Dental Journal. 2010;60(1):7-30. https://doi.org/10.1922/IDJ_2532Warnakulasuriya24.	177	17.70
44	Conway DI, Petticrew M, Marlborough H, Bertbiller J, Hashibe M, Macpherson LMD. Socioeconomic inequalities and oral cancer risk: a systematic review and meta-analysis of case-control studies. International Journal of Cancer. 2008;122(12):2811-9. https://doi.org/10.1002/ijc.23430.	176	14.67
45	Vainio H, Weiderpass E. Fruit and vegetables in cancer prevention. Nutrition and Cancer. 2006;54(1):111-42. https://doi.org/10.1207/s15327914nc5401_13.	176	12.57
46	Warnakulasuriya S. Living with oral cancer: epidemiology with particular reference to prevalence and life-style changes that influence survival. Oral Oncology. 2010;46(6):407-10. https://doi.org/10.1016/j.oraloncology.2010.02.015.	170	17.00
47	Day GL, Blot WJ. 2nd primary tumors in patients with oral-cancer. Cancer. 1992;70(1):14-9. https://doi.org/10.1002/1097-0142(19920701)70:1<14::AID-CNCR2820700103>3.0.CO;2-S.	167	5.96
48	Petti S. Lifestyle risk factors for oral cancer. Oral Oncology. 2009;45(4-5):340-50. https://doi.org/10.1016/j.oraloncology.2008.05.018.	166	15.09
49	Meyer MS, Joshipura K, Giovannucci E, Michaud DS. A review of the relationship between tooth loss, periodontal disease, and cancer. Cancer Causes & Control. 2008;19(9):895-907. https://doi.org/10.1007/s10552-008-9163-4.	164	13.67
50	Moore C. Cigarette smoking and cancer of mouth, pharynx, and larynx - continuing study. Journal of the American Medical Association. 1971;218(4):553-8. https://doi.org/10.1001/jama.218.4.553.	164	3.35
51	Gillison ML. Current topics in the epidemiology of oral cavity and oropharyngeal cancers. Head and Neck. 2007;29(8):779-92. https://doi.org/10.1002/hed.20573.	162	12.46
52	Castellsague X, Quintana MJ, Martinez MC, Nieto A, Sanchez MJ, Juan A, et al. The role of type of tobacco and type of alcoholic beverage in oral carcinogenesis. International Journal of Cancer. 2004;108(5):741-9. https://doi.org/10.1002/ijc.11627.	161	10.06
53	Trivedy CR, Craig G, Warnakulasuriya S. The oral health consequences of chewing areca nut. Addiction Biology. 2002;7(1):115-25. https://doi.org/10.1080/13556210120091482.	157	8.72
54	Schildt EB, Eriksson M, Hardell L, Magnuson A. Oral snuff, smoking habits and alcohol consumption in relation to oral cancer in a swedish case-control study. International Journal of Cancer. 1998;77(3):341-6. https://doi.org/10.1002/(SICI)1097-0215(19980729)77:3<341::AID-IJC6>3.3.CO;2-Q.	157	7.14
55	Miller CS, White DK. Human papillomavirus expression in oral mucosa, premalignant conditions, and squamous cell carcinoma - a retrospective review of the literature. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology. 1996;82(1):57-68. https://doi.org/10.1016/S1079-2104(96)80378-7.	157	6.54
56	Llewellyn CD, Linklater K, Bell J, Johnson NW, Warnakulasuriya S. An analysis of risk factors for oral cancer in young people: a case-control study. Oral Oncology. 2004;40(3):304-13. https://doi.org/10.1016/j.oraloncology.2003.08.015.	156	9.75
57	Day GL, Blot WJ, Austin DF, Bernstein L, Greenberg RS, Prestonmartin S, et al. Racial-differences in risk of oral and pharyngeal cancer - alcohol, tobacco, and other determinants. Journal of the National Cancer Institute. 1993;85(6):465-73. https://doi.org/10.1093/jnci/85.6.465.	154	5.70
58	Levi F, Pasche C, La Vecchia C, Lucchini F, Franceschi S, Monnier P. Food groups and risk of oral and pharyngeal cancer. International Journal of Cancer. 1998;77(5):705-9. https://doi.org/10.1002/(SICI)1097-0215(19980831)77:5<705::AID-IJC8>3.3.CO;2-Z.	153	6.95
59	Geisler SA, Olshan AF. GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: a mini-HuGE review. American Journal of Epidemiology. 2001;154(2):95-105. https://doi.org/10.1093/aje/154.2.95.	151	7.95
60	Luo J, Ye W, Zendehdel K, Adami J, Adami HO, Boffetta P, et al. Oral use of swedish moist snuff (snus) and risk for cancer of the mouth, lung, and pancreas in male construction workers: a retrospective cohort study. Lancet. 2007;369(9578):2015-20. https://doi.org/10.1016/S0140-6736(07)60678-3.	150	11.54
61	Hung HC, Chuang J, Chien YC, Chern HD, Chiang CP, Kuo YS, et al. Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer. Cancer Epidemiology Biomarkers & Prevention. 1997;6(11):901-5.	150	6.52
62	Jin LJ, Lamster IB, Greenspan JS, Pitts NB, Scully C, Warnakulasuriya S. Global burden of oral diseases: emerging concepts, management and interplay with systemic health. Oral Diseases. 2016;22(7):609-19. https://doi.org/10.1111/odi.12428.	149	37.25
63	Pelucchi C, Gallus S, Garavello W, Bosetti C, La Vecchia C. Alcohol and tobacco use, and cancer risk for upper aerodiaestive tract and liver. European Journal of Cancer Prevention. 2008;17(4):340-4. https://doi.org/10.1097/CEJ.0b013e3282f75e91.	146	12.17
64	Smith E, Hoffman HT, Summersgill KS, Kirchner HL, Turek LP, Haugen TH. Human papillomavirus and risk of oral cancer. Laryngoscope. 1998;108(7):1098-103. https://doi.org/10.1097/00005537-199807000-00027.	144	6.55
65	Sturgis EM, Wei QY, Spitz MR. Descriptive epidemiology and risk factors for head and neck cancer. Seminars In Oncology. 2004;31(6):726-33. https://doi.org/10.1053/j.seminoncol.2004.09.013.	141	8.81
66	Keller A, Terris M. The association of alcohol and tobacco with cancer of the mouth and pharynx. American Journal of Public Health and the Nations Health. 1965;55(10):1578-85. https://doi.org/10.2105/AJPH.55.10.1578.	140	2.55
67	Scully C, Bagan J. Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications. Oral Diseases. 2009;15(6):388-99. https://doi.org/10.1111/j.1601-0825.2009.01563.x.	137	12.45
68	Pelucchi C, Gallus S, Garavello W, Bosetti C, La Vecchia C. Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver. Alcohol Research & Health. 2006;29(3):193-8.	137	9.79
69	Palefsky JM. Human papillomavirus-related disease in men: not just a women's issue. Journal of Adolescent Health. 2010;46(4):S12-S9. https://doi.org/10.1016/j.jadohealth.2010.01.010.	135	13.50
70	Rodu B, Jansson C. Smokeless tobacco and oral cancer: a review of the risks and determinants. Critical Reviews In Oral Biology & Medicine. 2004;15(5):252-63. https://doi.org/10.1177/154411130401500502.	134	8.38
71	Rosenquist K, Wennerberg J, Schildt EB, Bladstrom A, Hansson BG, Andersson G. Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma: a population-based case-control study in southern Sweden. Acta Oto-Laryngologica. 2005;125(12):1327-36. https://doi.org/10.1080/00016480510012273.	133	8.87
72	Hashibe M, Morgenstern H, Cui Y, Tashkin DP, Zhang ZF, Cozen W, et al. Marijuana use and the risk of lung and upper aerodigestive tract cancers: results of a population-based case-control study. Cancer Epidemiology Biomarkers & Prevention. 2006;15(10):1829-34. https://doi.org/10.1158/1055-9965.EPI-06-0330.	132	9.43
73	Bouda M, Gorgoulis VG, Kastrinakis NG, Giannoudis A, Tsoli E, Danassi-Afentaki D, et al. High risk HPV types are frequently detected in potentially malignant and malignant oral lesions, but not in normal oral mucosa. Modern Pathology. 2000;13(6):644-53. https://doi.org/10.1038/modpathol.3880113.	131	6.55
74	Park JY, Muscat J, Ren Q, Schantz SP, Harwick RD, Stern JC, et al. CYP1A1 and GSTM1 polymorphisms and oral cancer risk. Cancer Epidemiology Biomarkers & Prevention. 1997;6(10):791-7.	131	5.70
75	Petti S, Masood M, Scully C. The magnitude of tobacco smoking-betel quid chewing-alcohol drinking interaction effect on oral cancer in south-east Asia. a meta-analysis of observational studies. PloS One. 2013;8(11):e78999. https://doi.org/10.1371/journal.pone.0078999.	130	18.57
76	Winn DM, Blot WJ, Mclaughlin JK, Austin DF, Greenberg RS, Prestonmartin S, et al. Mouthwash use and oral conditions in the risk of oral and pharyngeal cancer. Cancer Research. 1991;51(11):3044-7.	130	4.48
77	Maden C, Beckmann AM, Thomas DB, Mcknight B, Sherman KJ, Ashley RL, et al. Human papillomaviruses, herpes-simplex viruses, and the risk of oral-cancer in men. American Journal of Epidemiology. 1992;135(10):1093-102. https://doi.org/10.1093/oxfordjournals.aje.a116209.	127	4.54
78	Lajer CB, Nielsen FC, Friis-Hansen L, Norrild B, Borup R, Garnaes E, et al. Different mirna signatures of oral and pharyngeal squamous cell carcinomas: a prospective translational study. British Journal of Cancer. 2011;104(5):830-40. https://doi.org/10.1038/bjc.2011.29.	124	13.78
79	Zheng TZ, Boyle P, Hu HF, Duan J, Jiang PJ, Ma DQ, et al. Dentition, oral hygiene, and risk of oral cancer: a case-control study in Beijing, People's Republic of China. Cancer Causes & Control. 1990;1(3):235-41. https://doi.org/10.1007/BF00117475.	124	4.13
80	Schmidt BL, Kuczynski J, Bhattacharya A, Huey B, Corby PM, Queiroz ELS, et al. Changes in abundance of oral microbiota associated with oral cancer. PloS One. 2014;9(6):e106297. https://doi.org/10.1371/journal.pone.0098741.	121	20.17
81	Bundgaard T, Wildt J, Frydenberg M, Elbrond O, Nielsen JE. Case-control study of squamous-cell cancer of the oral cavity in Denmark. Cancer Causes & Control. 1995;6(1):57-67. https://doi.org/10.1007/BF00051681.	121	4.84
82	Freiman A, Bird G, Metelitsa AI, Barankin B, Lauzon GJ. Cutaneous effects of smoking. Journal of Cutaneous Medicine and Surgery. 2004;8(6):415-23. https://doi.org/10.1007/s10227-005-0020-8.	120	7.50
83	Merchant A, Husain SSM, Hosain M, Fikree FF, Pitiphat W, Siddiqui AR, et al. Paan without tobacco: an independent risk factor for oral cancer. International Journal of Cancer. 2000;86(1):128-31. https://doi.org/10.1002/(SICI)1097-0215(20000401)86:1<128::AID-IJC20>3.0.CO;2-M.	119	5.95
84	Tsantoulis PK, Kastrinakis NG, Tourvas AD, Laskaris G, Gorgoulis VG. Advances in the biology of oral cancer. Oral Oncology. 2007;43(6):523-34. https://doi.org/10.1016/j.oraloncology.2006.11.010.	118	9.08
85	Ribeiro KB, Levi JE, Pawlita M, Koifman S, Matos E, Eluf-Neto J, et al. Low human papillomavirus prevalence in head and neck cancer: results from two large case-control studies in high-incidence regions. International Journal of Epidemiology. 2011;40(2):489-502. https://doi.org/10.1093/ije/dyq249.	116	12.89
86	Warnakulasuriya S, Sutherland G, Scully C. Tobacco, oral cancer, and treatment of dependence. Oral Oncology. 2005;41(3):244-60. https://doi.org/10.1016/j.oraloncology.2004.08.010.	116	7.73
87	Marron M, Boffetta P, Zhang ZF, Zaridze D, Wunsch V, Winn DM, et al. Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk. International Journal of Epidemiology. 2010;39(1):182-96. https://doi.org/10.1093/ije/dyp291.	114	11.40
88	Hashibe M, Straif K, Tashkin DP, Morgenstern H, Greenland S, Zhang ZF. Epidemiologic review of marijuana use and cancer risk. Alcohol. 2005;35(3):265-75. https://doi.org/10.1016/j.alcohol.2005.04.008.	113	7.53
89	Boehm K, Borrelli F, Ernst E, Habacher G, Hung SK, Milazzo S, et al. Green tea (camellia sinensis) for the prevention of cancer. Cochrane Database of Systematic Reviews. 2009;Blank(3):CD005004. https://doi.org/10.1002/14651858.CD005004.pub2.	112	10.18
90	Sreelekha TT, Ramadas K, Pandey M, Thomas G, Nalinakumari KR, Pillai MR. Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer. Oral Oncology. 2001;37(7):593-8. https://doi.org/10.1016/S1368-8375(01)00028-8.	112	5.89
91	Muwonge R, Ramadas K, Sankila R, Thara S, Thomas G, Vinoda J, et al. Role of tobacco smoking, chewing and alcohol drinking in the risk of oral cancer in Trivandrum, India: a nested case-control design using incident cancer cases. Oral Oncology. 2008;44(5):446-54. https://doi.org/10.1016/j.oraloncology.2007.06.002.	111	9.25
92	Hatsukami DK, Lemmonds C, Tomar SL. Smokeless tobacco use: harm reduction or induction approach? Preventive Medicine. 2004;38(3):309-17. https://doi.org/10.1016/j.ypmed.2003.10.006.	111	6.94
93	Lissowska J, Pilarska A, Pilarski P, Samolczyk-Wanyura D, Piekarczyk J, Bardin-Mikolajczak A, et al. Smoking, alcohol, diet, dentition and sexual practices in the epidemiology of oral cancer in Poland. European Journal of Cancer Prevention. 2003;12(1):25-33. https://doi.org/10.1097/00008469-200302000-00005.	111	6.53
94	Katoh T, Kaneko S, Kohshi K, Munaka M, Kitagawa K, Kunugita N, et al. Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer. International Journal of Cancer. 1999;83(5):606-9. https://doi.org/10.1002/(SICI)1097-0215(19991126)83:5<606::AID-IJC6>3.0.CO;2-P.	110	5.24
95	Llewellyn CD, Johnson NW, Warnakulasuriya S. Risk factors for oral cancer in newly diagnosed patients aged 45 years and younger: a case-control study in southern England. Journal of Oral Pathology & Medicine. 2004;33(9):525-32. https://doi.org/10.1111/j.1600-0714.2004.00222.x.	109	6.81
96	Hayes RB, Bravo-Otero E, Kleinman DV, Brown LM, Fraumeni JF, Harty LC, et al. Tobacco and alcohol use and oral cancer in Puerto Rico. Cancer Causes & Control. 1999;10(1):27-33. https://doi.org/10.1023/A:1008876115797.	109	5.19
97	Mills CA, Porter MM. Tobacco smoking habits and cancer of the mouth and respiratory system. Cancer Research. 1950;10(9):539-42.	109	1.56
98	Waziry R, Jawad M, Ballout RA, Al Akel M, Akl EA. The effects of waterpipe tobacco smoking on health outcomes: an updated systematic review and meta-analysis. International Journal of Epidemiology. 2017;46(1):32-43. https://doi.org/10.1093/ije/dyw021.	108	36.00
99	Warnakulasuriya S. Causes of oral cancer - an appraisal of controversies. British Dental Journal. 2009;207(10):471-5. https://doi.org/10.1038/sj.bdj.2009.1009.	108	9.82
100	Sato M, Sato T, Izumo T, Amagasa T. Genetic polymorphism of drug-metabolizing enzymes and susceptibility to oral cancer. Carcinogenesis. 1999;20(10):1927-31. https://doi.org/10.1093/carcin/20.10.1927.	108	5.14

Study design	Articles	Citations (WoS-CC)	Citation ratio^a a Citation ratio: number of citations per number of articles in each study design;	Years of publication^b b Years of publication: sum of years since publication in each study design;	Citation density^c c Citation density: citation ratio per sum of years since publication in each study design.
Case-control study	39	8,583	220.08	979	0.22
Narrative review	29	7,486	258.14	416	0.62
Systematic review	14	2,338	167.00	197	0.85
Systematized review	10	2,062	206.20	153	1.35
Cohort study	5	1,302	260.40	108	2.41
Cross-sectional study	3	444	148.00	38	3.89
Total	100	22,215	222.15	1,891	0.12

Rank	Author	Affiliation	Articles	Citations
1	Franceschi S.	International Agency for Research on Cancer	10	3,171
2	Warnakulasuriya S.	King's College London	10	2,945
3	Boffetta P.	International Agency for Research on Cancer	9	2,537
4	Herrero R.	Costa Rican Foundation for Training in Health Sciences	8	2,740
5	Winn D. M.	National Cancer Institute	8	2,314
6	Scully C.	University College London	8	1,264
7	La Vecchia C.	Mario Negri Institute for Pharmacological Research	7	1,960
8	Brennan P.	International Agency for Research on Cancer	7	1,954
9	Hashibe M.	International Agency for Research on Cancer	7	1,868
10	Castellsague X.	L’Hospitalet de Llobregat	6	2,445
11	Curado M. P.	Hospital Araujo Jorge	6	1,821
12	Schwartz S. M.	Fred Hutchinson Cancer Research Center	5	1,857
13	Fernandez L.	Institute of Oncology and Radiobiology	5	1,824
14	Levi F.	Centre Hospitalier Universitaire Vaudois	5	1,677
15	Smith E.	University of Iowa	5	1,591

Rank	Institution	Country	Articles	Citations
1	International Agency for Research on Cancer	France	10	2,699
2	King's College London	England	9	2,796
3	National Cancer Institute	USA	4	925
4	Harvard University	USA	3	696
5	University of California	USA	3	639
6	University College London	England	3	566
7	Sapienza Università di Roma	Italy	3	475
8	Fred Hutchinson Cancer Research Center	USA	2	537
9	University of Turku	Finland	2	454
10	University of Kentucky	USA	2	452
11	Mario Negri Institute for Pharmacological Research	Italy	2	424
12	University of Texas	USA	2	368
13	University of Athens	Greece	2	249
14	Costa Rican Foundation for Training in Health Sciences	Costa Rica	1	837
15	Medical University of South Carolina	USA	1	734

Sociedade Brasileira de Pesquisa Odontológica - SBPqO Av. Prof. Lineu Prestes, 2227, 05508-000 São Paulo SP - Brazil, Tel. (55 11) 3044-2393/(55 11) 9-7557-1244 - São Paulo - SP - Brazil
E-mail: office.bor@ingroup.srv.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] Corresponding Author: Elena Riet Correa Rivero. E-mail: riet.elena@gmail.com

Brasil

Brasil

Top 100 most-cited articles on intraoral squamous cell carcinoma and its risk factors: a bibliometric study

Abstract: