A greenhouse experiment was conducted to determine the pathogenicity of 15 different isolates of Ceratocystis fimbriata Ell. & Halst. in cocoa (Theobroma cacao L.) plants. The isolates were obtained from Cajanus cajans L., Acacia decurrens Willd, Crotalaria juncea L. and Mangifera indica L. Potted cocoa plants (10 months old) representing nine different hybrids were used: SCA 6 x ICS 8, SCA 6 x UF 667, SCA 12 x UF 677, SCA 12 x UF 667, IMC 67 x UF 668, ICS 45 x SCA 6, ISC 45 x SCA 12, ICS 95 x SCA 12 and UF 677 x SCA 6. Evaluation of damage was made visually at 120 days after inoculation. The results indicated no differences between control and inoculated plants.