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Factors related to clinical outcomes and survival time in chronic kidney disease patients on hemodialysis

Abstract

Background

Hemodialysis usually lasts until the end of life or until kidney transplantation.

Objective

to verify the factors related to clinical outcomes and survival of chronic renal patients in hemodialysis at a clinic in the south of Santa Catarina

Method

A retrospective cohort study. Survival was assessed by Kaplan-Meier curves and outcome-related factors were assessed using Cox regression, with comparisons using Hazard Ratio (HR) and 95% confidence intervals.

Results

Among the 120 patients, the mean age was 61.8 (± 13.9) years. The main sector of referral for hemodialysis was the nephrologist (33.3%). The main underlying diseases identified were hypertension (60.8%) and Diabetes Mellitus (29.2%). Death was recorded in 44.2% of the patients, and seven (5.8%) performed a transplant. Survival decreased from 76.1% in one month to 49.3% in one year of treatment. Referral by intensive care unit (HR 18.1 95% CI 4.49-72.8) and Basic Health Unit (HR 9.27 95% CI 1.48-58.2) were associated with death, besides of higher values of initial calcium (HR 2.36 95%CI 1.21-4.62) and lower final creatinine (HR 0.69 95%CI 0.55-0.87).

Conclusion

The main outcome was death, being the patient´s survival, evaluated in a short term, lower than expected, suggesting late referral to the substitutive treatment.

Keywords:
chronic renal insufficiency; hemodialysis; nephrology; chronic disease; survival

Instituto de Estudos em Saúde Coletiva da Universidade Federal do Rio de Janeiro Avenida Horácio Macedo, S/N, CEP: 21941-598, Tel.: (55 21) 3938 9494 - Rio de Janeiro - RJ - Brazil
E-mail: cadernos@iesc.ufrj.br