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Neurocognitive disorders and medication used by the institutionalized elderly population of the interior of Minas Gerais, Brazil

Abstract

Background

Institutionalized elderly are at greater risk of prescribing five or more medications and consequently of higher occurence of adverse events, as they have limiting health problems, frailty and low functionality. This risk is even greater if they also have cognitive decline.

Objective

To determine the prevalence of cognitive disorders (CDs) and its association with the medication used by the institutionalized elderly population of the interior of Minas Gerais, Brazil.

Method

Descriptive cross-sectional study for analysis of medical records of institutionalized elderly with or without CDs, according to validated tests. The medicine used and the potentially inappropriate medications (PIMs) were determined as per the Beers criteria (2015).

Results

Eighty eight elderly people, with mean age of 77.6 (9.2) years, were included. CD prevalence was 75% higher in females (82.5%, p = 0.01) and in older age groups, with 80 years and above (85%, p = 0.04). Antiemetics and proton pump inhibitors were significantly more used by the elderly with CDs. The prevalence of polypharmacy was 69.3%, 71 elderlies (80.7%) used at least one PIM, and a higher prevalence of PIM use was observed in elderly people of 60 to 79 years old (p = 0.004). The elderly who used at least one PIM was also observed to use a higher number of medications (p = 0.014).

Conclusion

CDs was found to be related to the higher use of antiemetics and proton pump inhibitors, but not to the use of PIMs in regards to the institutionalized elderlies. Furthermore, a high prevalence of polypharmacy and PIMs were detected in the prescriptions of the institutionalized elderly subjects.

Keywords:
cognitive deficit; potentially inappropriate medication; elderly; institutionalized

Instituto de Estudos em Saúde Coletiva da Universidade Federal do Rio de Janeiro Avenida Horácio Macedo, S/N, CEP: 21941-598, Tel.: (55 21) 3938 9494 - Rio de Janeiro - RJ - Brazil
E-mail: cadernos@iesc.ufrj.br