Tissue engineering involves the manipulation and the development of cells aiming to create and/or regenerate organs and tissues. Function failure of injuried tissues is a severe animal health problem, nevertheless, the transplantation has been indicated to treat and replace the biological function. A large amount of animals are affected by those problems, and for this reason it is necessary to find alternative therapies to treat bone losses. Studies such those involving tissue engineering have contributed to regenerative medicine advances, to developed synthetic and natural scaffolds. To pursue these objectives, specific combinations of autologous or alogenous bone marrow progenitor cells seeded over a three-dimension scaffold with adequate properties, creating a hybrid material that can be modulated to patient reinsertion. In this review, information about synthetic and natural biological materials indicated to bone grats, combined or not with progenitor cells, aiming to stimulate bone healing process are presented.
Scaffold; biological behaviour; bone repair; progenitor cells
