Gao et al. (2000)Gao, G., Wang, S., & Zhang, J. (2000). Study on beta 2 adrenergic receptor genetic polymorphisms in asthmatics in the people of the Han nationality of northern China. Zhonghua Jie He He Hu Xi Za Zhi, 23(2), 93-97. PMid:11778498.
|
Beijing |
Mixed |
58 |
89 |
14 |
26 |
18 |
12 |
68 |
9 |
24.98 |
0.000 |
Liao et al. (2001)Liao, W., Li, W. M., Zhao, C. M., Guang, L. X., Yin, X. J., Ai, Y. P., & Xi, M. (2001). Preliminary Study on the relationship between b2-adrenergic receptors genetic polymorphisms and asthma in children of Han nationality of Chongqing. Journal of Third Military Medical University, 23, 968-971.
|
Chongqing |
Children |
50 |
100 |
12 |
27 |
11 |
35 |
46 |
19 |
0.31 |
0.577 |
Xing et al. (2001)Xing, J., Wang, C., Liu, J. Z., Yan, M., Huang, K. W., & Xiao, B. (2001). Association of receptor gene polymorphisms with asthma in Northern Chinese Han Population. Zhonghua Nei Ke Za Zhi, 40, 340-342.
|
Beijing |
Adult |
100 |
100 |
9 |
62 |
29 |
29 |
55 |
16 |
1.41 |
0.234 |
Wang et al. (2001)Wang, Z., Chen, C., Niu, T., Wu, D., Yang, J., Wang, B., Fang, Z., Yandava, C. N., Drazen, J. M., Weiss, S. T., & Xu, X. (2001). Association of asthma with beta(2)-adrenergic receptor gene polymorphism and cigarette smoking. American Journal of Respiratory and Critical Care Medicine, 163(6), 1404-1409. http://dx.doi.org/10.1164/ajrccm.163.6.2001101. PMid:11371409. http://dx.doi.org/10.1164/ajrccm.163.6.2...
|
Anhui |
Adult |
101 |
136 |
25 |
54 |
22 |
38 |
64 |
34 |
0.46 |
0.499 |
Dai et al. (2002)Dai, L. M., Wang, Z. L., Zhang, Y. P., Li, W., Zhao, Z. H., & Liu, L. (2002). Association of beta2 receptor gene polymorphisms with lung function in asthma patients. Zhonghua Jie He He Hu Xi Za Zhi, 25, 554-555.
|
Sichuan |
Adult |
87 |
94 |
33 |
33 |
21 |
36 |
33 |
25 |
7.80 |
0.005 |
Leung et al. (2003)Leung, T. F., Tang, N. L., Chan, I. H., Li, A. M., Ha, G., Lam, C. W., & Fok, T. F. (2003). Distribution in allele frequencies of predisposition-to-atopy genotypes in Chinese children. Pediatric Pulmonology, 34(6), 419-424. http://dx.doi.org/10.1002/ppul.10210. PMid:12422339. http://dx.doi.org/10.1002/ppul.10210...
|
Hong Kong |
Children |
76 |
70 |
25 |
38 |
13 |
22 |
37 |
11 |
0.49 |
0.483 |
Lin et al. (2003)Lin, Y. C., Lu, C. C., Shen, C. Y., Lei, H. Y., Guo, Y. L., & Su, H. J. (2003). Roles of genotypes of beta2-adrenergic receptor in the relationship between eosinophil counts and lung function in Taiwanese adolescents. The Journal of Asthma, 40(3), 265-272. http://dx.doi.org/10.1081/JAS-120018323. PMid:12807170. http://dx.doi.org/10.1081/JAS-120018323...
|
Taiwan |
Children |
80 |
69 |
34 |
35 |
11 |
27 |
25 |
17 |
4.66 |
0.031 |
Wang et al. (2004)Wang, W., Wufuer, H. M. T. L., Shabiti, Y. L. H. M. J., Xiang, Y. B., & Abula, A. B. L. K. M. (2004). Association between the genetic polymorphisms of b2-adrenergic receptor gene and the asthma susceptibility and clinical phenotypes in Uygur population. Journal of Cardiovascular and Pulmonary Diseases, 23, 147-152.
|
Xinjiang |
Adult |
123 |
89 |
48 |
59 |
16 |
26 |
54 |
9 |
5.99 |
0.014 |
Gao et al. (2004)Gao, J. M., Lin, Y. G., Qiu, C. C., Liu, Y. W., Ma, Y., & Liu, Y. (2004). Beta2-adrenergic receptor gene polymorphism in Chinese Northern asthmatics. Chinese Medical Sciences Journal, 19(3), 164-169. PMid:15506640.
|
Beijing |
Adult |
125 |
96 |
38 |
59 |
28 |
35 |
53 |
8 |
3.80 |
0.051 |
Cui et al. (2007)Cui, L. Y., Liu, X. H., Gao, L. X., & Fan, D. S. (2007). Study on the Association between b2-adrenergic Receptor Genetic polymorphisms and asthma in the population of Inner Mongolia. Chinese journal of Clinical Medicin, 14, 477-481.
|
Inner Mongolia |
Adult |
72 |
60 |
9 |
55 |
8 |
12 |
39 |
9 |
5.52 |
0.019 |
Ye et al. (2011)Ye, X. W., Feng, D. X., Zhang, X. Y., Yu, H., & Xu, M. (2011). Study on the Relationship between b2-adrenergic Receptor Genetic polymorphisms and asthma a in Miao Nationality. The Journal of Medical Research, 40, 83-85.
|
Guizhou |
Adult |
31 |
37 |
5 |
19 |
7 |
5 |
26 |
6 |
6.11 |
0.013 |
Zhang et al. (2008)Zhang, X. Y., Zhao, W. L., Gui, Q., He, N. H. (2008). Relationship between genetic polymorphisms of b2-adrenergic receptor and childhood asthma. Journal of Clinical Pediatrics, 26, 399-402.
|
Chongqing |
Children |
217 |
50 |
81 |
111 |
25 |
19 |
23 |
8 |
0.06 |
0.814 |
Yang et al. (2012)Yang, Z., Zhang, H., Wang, W., Yin, Y., Wang, J., Zhang, L., Wu, Y. F., & Jiang, F. (2012). Effect of b2-adrenergic receptor polymorphisms on childhood asthma and therapeutic efficacy of long acting b2-agonist. Journal of Clinical Pediatrics, 30, 739-743.
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Shanghai |
Children |
212 |
52 |
78 |
104 |
30 |
24 |
23 |
5 |
0.02 |
0.880 |
Feng et al. (2004)Feng, D. X., Ye, X. W., Zhang, X. Y., Yu, H., Diao, X. Y., Zhang, X. R., & Luo, R. R. (2004). Study on b2-adrenergic Receptor Genetic Polymorphisms and Asthma. Journal of Modern Clinical Medical Bioengineering, 10, 5-7.
|
Guizhou |
Adult |
74 |
39 |
13 |
35 |
26 |
6 |
28 |
5 |
7.44 |
0.006 |
He et al. (2012)He, X. Q., Li, F. X., Tan, J. Y., & Yang, X. X. (2012). Association of single nucleotide polymorphisms of ADRB2 Arg16Gly with asthma in southern Chinese population. Immunological Journal, 28, 687-690, 702.
|
Guangdong |
Adult |
171 |
148 |
32 |
130 |
9 |
50 |
66 |
32 |
1.33 |
0.249 |
Xie et al. (2008)Xie, Y., Yang, Z. Z., Chai, B. C. (2008). Relationship of Genetic Polymorphisms of b2 -Adrenergic Receptor and Asthma in Children in Shanghai Area. Journal of Applied Clinical Pediatrics, 23, 272-273.
|
Shanghai |
Children |
57 |
62 |
14 |
37 |
6 |
21 |
34 |
7 |
1.50 |
0.220 |
Liu et al. (2009)Liu, L., Fang, L. Z., & Dai, L. M. (2009). Combination Effect of Gene Polymorphisms in 16 Position of b2-adenergic Receptor and Cigarette Smoking on Asthma in Chinese Han Individuals. Medical Recapitulate, 15, 1247-1250.
|
Yunnan |
Adult |
120 |
120 |
27 |
59 |
34 |
23 |
71 |
26 |
4.07 |
0.044 |
Shi & Zhou (2008) Shi, X. H., & Zhou, J. P. (2008). Association of IL-13 and beta2 receptor gene polymorphisms with asthma. Shandong Yiyao, 48, 119-121.
|
Shandong |
Mixed |
48 |
48 |
22 |
19 |
7 |
10 |
25 |
13 |
0.10 |
0.751 |
Tuerxun et al. (2007)Tuerxun, K. L. B. N., Shabiti, Y. L. H. M., Wang, W., & Wufuer, H. M. T. L. (2007). Study on the b2AR polymorphism in asthmatic abnormal black savda patients. Xinjiang Yike Daxue Xuebao, 30, 945-948.
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Xinjiang |
Adult |
76 |
89 |
13 |
36 |
27 |
26 |
54 |
9 |
5.99 |
0.014 |
Zheng et al. (2012)Zheng, B. Q., Wang, G. L., Yang, S., Lu, Y. Q., Liu, R. J., & Li, Y. (2012). Study of genetic susceptibility in 198 children with asthma. Zhongguo Dang Dai Er Ke Za Zhi, 14(11), 811-814. PMid:23146724.
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Guangdong |
Children |
198 |
110 |
71 |
99 |
28 |
31 |
55 |
24 |
0.00 |
0.966 |
Fu et al. (2011)Fu, W. P., Zhao, Z. H., Zhong, L., Sun, C., Fang, L. Z., Liu, L., Zhang, J. Q., Wang, L., Shu, J. K., Wang, X. M., & Dai, L. M. (2011). Relationship between polymorphisms in the 5′ leader cistron, positions 16 and 27 of the adrenergic β2 receptor gene and asthma in a Han population from southwest China. Respirology (Carlton, Vic.), 16(8), 1221-1227. http://dx.doi.org/10.1111/j.1440-1843.2011.02028.x. PMid:21801278. http://dx.doi.org/10.1111/j.1440-1843.20...
|
Yunnan |
Adult |
238 |
265 |
85 |
88 |
65 |
106 |
92 |
67 |
22.33 |
0.000 |
Qiu et al. (2010)Qiu, Y. Y., Zhang, X. L., Qin, Y., Yin, K. S., & Zhang, D. P. (2010). Beta(2)-adrenergic receptor haplotype/polymorphisms and asthma susceptibility and clinical phenotype in a Chinese Han population. Allergy and Asthma Proceedings, 31(5), 91-97. http://dx.doi.org/10.2500/aap.2010.31.3371. PMid:20929600. http://dx.doi.org/10.2500/aap.2010.31.33...
|
Jiangsu |
Adult |
201 |
276 |
77 |
85 |
39 |
88 |
135 |
53 |
0.01 |
0.924 |
Chan et al. (2008)Chan, I. H., Tang, N. L., Leung, T. F., Huang, W., Lam, Y. Y., Li, C. Y., Wong, C. K., Wong, G. W., & Lam, C. W. (2008). Study of genegene interactions for endophenotypic quantitative traits in Chinese asthmatic children. Allergy, 63(8), 1031-1039. http://dx.doi.org/10.1111/j.1398-9995.2008.01639.x. PMid:18691306. http://dx.doi.org/10.1111/j.1398-9995.20...
|
Hong Kong |
Children |
295 |
173 |
101 |
135 |
59 |
51 |
89 |
33 |
0.28 |
0.597 |
Wang et al. (2009)Wang, J. Y., Liou, Y. H., Wu, Y. J., Hsiao, Y. H., & Wu, L. S. (2009). An association study of 13 SNPs from seven candidate genes with pediatric asthma and a preliminary study for genetic testing by multiple variants in Taiwanese population. Journal of Clinical Immunology, 29(2), 205-209. http://dx.doi.org/10.1007/s10875-008-9256-6. PMid:18931892. http://dx.doi.org/10.1007/s10875-008-925...
|
Taiwan |
Children |
442 |
510 |
138 |
207 |
97 |
173 |
250 |
87 |
0.04 |
0.837 |
Pan et al. (2005)Pan, Y. P., Zhou, S. L., Kuang, J. L., Rao, W. H. (2005). Study on the relationship between the genetic polymorphisms of β2-adrenergic receptor gene and asthma. Acta academiae Med Jiangxi, 45, 44-47.
|
Jiangxi |
Adult |
45 |
45 |
10 |
21 |
14 |
6 |
34 |
5 |
11.79 |
0.001 |
Liu et al. (2006)Liu, X. H., Cui, L. Y., Li, D. W., Gao, L. X., & Pan, D. S. (2006). Study on β2-adrenergic receptor genetic polymorphisms in asthmatics. Chin J Pract Inter Med, 26, 1526-1529.
|
Inner Mongolia |
Adult |
42 |
30 |
6 |
34 |
2 |
6 |
20 |
4 |
3.45 |
0.063 |
Qiu & Yin (2008) Qiu, Y. Y., & Yin, K. S. (2008). Relationship between bata2-adrenergic receptor haplotype/polymorphisms and bronchial asthma in the elderly. Shiyong Laonian Yixue, 22, 105-107.
|
Jiangsu |
Adult |
70 |
112 |
25 |
31 |
14 |
34 |
55 |
23 |
0.01 |
0.930 |
Hua et al. (2008)Hua, L., Bao, Y. X., Lv, J., Dong, X. Y., Jin, Z. Q., Tong, Q. T., & Zhang, H. B. (2008). Association of single nucleotide polymorphisms in IL-13 and β2-adrenoreceptor genes with children asthma. J Clin Pediatr, 26, 30-32.
|
Shanghai |
Children |
96 |
96 |
43 |
38 |
15 |
23 |
50 |
23 |
0.17 |
0.683 |
Li et al. (2009)Li, H., Xiaoyan, D., Quanhua, L., Jie, L., & Yixiao, B. (2009). Single-nucleotide polymorphisms in genes predisposing to asthma in children of Chinese Han nationality. Journal of Investigational Allergology & Clinical Immunology, 19(5), 391-395. PMid:19862939.
|
Shanghai |
Children |
192 |
192 |
86 |
76 |
30 |
46 |
100 |
46 |
0.33 |
0.564 |
Chen et al. (2014)Chen, H. F., Zhang, D. P., Qiu, Y. Y., & Xiao, Y. L. (2014). Association between ADRB2 gene polymorphisms/haplotype and asthma in a Chinese Han population. Acta Univ Med Nanjing, 34, 323-329.
|
Jiangsu |
Adult |
379 |
435 |
132 |
185 |
62 |
129 |
221 |
85 |
0.31 |
0.579 |
Liu et al. (2014)Liu, Z. Q., Jiao, Y., Liu, C. J., Zhang, H. C., & Hu, B. R. (2014). Association between polymorphisms and haplotypes of the beta-2 adrenergic receptor gene and asthma in a Chinese Han population. International Journal of Clinical and Experimental Medicine, 7(10), 3812-3817. PMid:25419437.
|
Heilongjiang |
Adult |
429 |
483 |
150 |
209 |
70 |
153 |
237 |
93 |
0.01 |
0.943 |
Hua et al. (2016)Hua, L., Zuo, X. B., Bao, Y. X., Liu, Q. H., Li, J. Y., Lv, J., Fang, D. Z., Lin, Q., Bao, J., & Ji, R. X. (2016). Four-locus gene interaction between IL13, IL4, FCER1B, and ADRB2 for asthma in Chinese Han children. Pediatric Pulmonology, 51(4), 364-371. http://dx.doi.org/10.1002/ppul.23322. PMid:26613553. http://dx.doi.org/10.1002/ppul.23322...
|
Shanghai |
Children |
1000 |
1000 |
396 |
448 |
156 |
308 |
500 |
192 |
0.19 |
0.666 |
Tian et al. (2016)Tian, M., Liang, H., Qin, Q. Z., Zhang, W. X., & Zhang, S. S. (2016). ADRB2 polymorphisms in allergic asthma in Han Chinese children. International Forum of Allergy & Rhinology, 6(4), 367-372. http://dx.doi.org/10.1002/alr.21673. PMid:26633084. http://dx.doi.org/10.1002/alr.21673...
|
Jiangsu |
Children |
298 |
304 |
104 |
145 |
49 |
90 |
154 |
60 |
0.16 |
0.687 |
Guo et al. (2016)Guo, X., Zheng, H., Mao, C., Guan, E., & Si, H. (2016). An association and meta-analysis study of 4 SNPs from beta-2 adrenergic receptor (ADRB2) gene with risk of asthma in children. Asian Pacific Journal of Allergy and Immunology, 34(1), 11-20. PMid:26994621.
|
Shandong |
Children |
340 |
340 |
84 |
218 |
38 |
116 |
184 |
40 |
6.60 |
0.010 |