Acessibilidade / Reportar erro

Effect of diet, statin, and ômega-3 fatty acids on the blood pressure and lipidemia in humans

Cardiovascular diseases are responsible for the high mortality rate in many countries, therefore, they have been widely studied recently. The objective of this research was to evaluate the concentration of cholesterol and its fractions, triglycerides and blood pressure in humans. This study was divided into three treatments (placebo, statin, and ômega-3) with a 1200 calorie diet per day for all groups of eight patients. The following parameters were evaluated on day 0 and day 30: anthropometry (weight); clinical assessment (arterial pressure), and biochemistry (total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides). The findings show that in the diet treatment there was weight loss, decrease of total cholesterol, HDL-cholesterol, triglycerides, SAP, and DAP, and increase of LDL-cholesterol. In the statin treatment there was weight loss, decrease of total cholesterol, LDL-cholesterol, triglycerides, SAP, and DA, and increase of HDL-cholesterol. In the ômega-3 treatment it was verified weight loss, total cholesterol, LDL-cholesterol, and triglycerides; increase of values of SAP and DAP, and the levels of HDL-cholesterol remained constant.

cardiovascular diseases; lipids; drugs; blood pressure; public health


Sociedade Brasileira de Ciência e Tecnologia de Alimentos Av. Brasil, 2880, Caixa Postal 271, 13001-970 Campinas SP - Brazil, Tel.: +55 19 3241.5793, Tel./Fax.: +55 19 3241.0527 - Campinas - SP - Brazil
E-mail: revista@sbcta.org.br