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Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects

SINTOMAS NEUROPSIQUIÁTRICOS NA DEMÊNCIA VASCULAR: ASPECTOS CLÍNICOS E EPIDEMIOLÓGICOS

ABSTRACT

Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases.

Objective:

To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia.

Methods:

A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS).

Results:

81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI: 1.36-27.9, p = 0.02).

Conclusion:

Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS.

Key words:
vascular dementia; elderly; behavioral symptoms; neuropsychiatric symptoms

Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento R. Vergueiro, 1353 sl.1404 - Ed. Top Towers Offices, Torre Norte, São Paulo, SP, Brazil, CEP 04101-000, Tel.: +55 11 5084-9463 | +55 11 5083-3876 - São Paulo - SP - Brazil
E-mail: revistadementia@abneuro.org.br | demneuropsy@uol.com.br