ABSTRACT:
This study presents the design and analysis of a modelling-based activity about gene expression framed in a sequence about genetic diseases for secondary students. The research is part of a broader investigation embedded in a thesis on students' enactment of scientific practices in a Genetics learning context. We propose modelling as a way to visualize and to better understand the mechanisms involved in gene expression.
The research questions are: 1) How are the material models that secondary students elaborate in order to explain gene expression?; 2) to what extent do t hey explain gene expression using their material models and are able to relate them with sickle cell disease?
The results show that all groups mobilize genetic ideas and notions to build their models, although in some cases they limit to name and locate the elements involved in gene expression. On the other hand, modelling gene expression using the kit allows the students to construct an explanation about the mechanisms participating in gene expression. The five groups expanded and improved their models when they had to justify them in their writing reports or orally. This reveals the potential of using a modelling approach based on the stages proposed by Justi (2006).
Keywords:
the gene expression model; scientific practices; modelling; genetic diseases.
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