SR62 |
mRNA processing/stability |
Názer et al. (2011)Názer E, Verdún RE and Sánchez DO (2011) Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosoma cruzi. PLoS One 6:e19920.
|
SR-related |
ZC3H39 |
Regulator of a specific subset of mRNAs |
Alves et al., 2014Alves LR, Oliveira C, Mörking PA, Kessler RL, Martins ST, Romagnoli BA, Marchini FK and Goldenberg S (2014) The mRNAs associated to a zinc finger protein from Trypanosoma cruzi shift during stress conditions. RNA Biol 11:921-933.
|
CCCH |
UBP1 |
mRNA destabilizing factor |
D’Orso and Frasch (2002)D’Orso I and Frasch AC (2002) TcUBP-1, an mRNA destabilizing factor from trypanosomes, homodimerizes and interacts with novel AU-rich element- and Poly(A)-binding proteins forming a ribonucleoprotein complex. J Biol Chem 277:50520-50528.
|
RRM |
UBP2 |
mRNA destabilizing factor |
D’Orso and Frasch (2002)D’Orso I and Frasch AC (2002) TcUBP-1, an mRNA destabilizing factor from trypanosomes, homodimerizes and interacts with novel AU-rich element- and Poly(A)-binding proteins forming a ribonucleoprotein complex. J Biol Chem 277:50520-50528.
|
RRM |
PUF6 |
mRNA destabilizing factor |
Dallagiovanna et al. (2008)Dallagiovanna B, Correa A, Probst CM, Holetz F, Smircich P, de Aguiar AM, Mansur F, da Silva CV, Mortara RA, Garat G, et al. (2008) Functional genomic characterization of mRNAs associated with TcPUF6, a pumilio-like protein from Trypanosoma cruzi. J Biol Chem 283:8266-8273.
|
Pumilio |
ZFP1 |
Involved in differentiation |
Mörking et al. (2004)Mörking PA, Dallagiovanna BM, Foti L, Garat B, Picchi GF, Umaki AC, Probst CM, Krieger MA, Goldenberg S and Fragoso SP (2004) TcZFP1: a CCCH zinc finger protein of Trypanosoma cruzi that binds poly-C oligoribonucleotides in vitro. Biochem Biophys Res Commun 319:169-177.
|
CCCH |
ZFP2 |
Involved in differentiation |
Mörking et al. (2004Mörking PA, Dallagiovanna BM, Foti L, Garat B, Picchi GF, Umaki AC, Probst CM, Krieger MA, Goldenberg S and Fragoso SP (2004) TcZFP1: a CCCH zinc finger protein of Trypanosoma cruzi that binds poly-C oligoribonucleotides in vitro. Biochem Biophys Res Commun 319:169-177., 2012Mörking PA, Rampazzo RC, Walrad P, Probst CM, Soares MJ, Gradia DF, Pavoni DP, Krieger MA, Matthews K, Goldenberg S, et al. (2012) The zinc finger protein TcZFP2 binds target mRNAs enriched during Trypanosoma cruzi metacyclogenesis. Mem Inst Oswaldo Cruz 107:790-799.) |
CCCH |
ZFP3 |
Involved in differentiation, translation regulator |
Mörking et al. (2004)Mörking PA, Dallagiovanna BM, Foti L, Garat B, Picchi GF, Umaki AC, Probst CM, Krieger MA, Goldenberg S and Fragoso SP (2004) TcZFP1: a CCCH zinc finger protein of Trypanosoma cruzi that binds poly-C oligoribonucleotides in vitro. Biochem Biophys Res Commun 319:169-177.
|
CCCH |
RBP40 |
Regulator of a specific subset of mRNAs |
Guerra-Slompo et al. (2012)Guerra-Slompo EP, Probst CM, Pavoni DP, Goldenberg S, Krieger MA and Dallagiovanna B (2012) Molecular characterization of the Trypanosoma cruzi specific RNA binding protein TcRBP40 and its associated mRNAs. Biochem Biophys Res Commun 420:302-307.
|
RRM |
RBP19 |
Involved in differentiation |
Pérez-Díaz et al. (2012Pérez-Díaz L, Correa A, Moretão MP, Goldenberg S, Dallagiovanna B and Garat B (2012) The overexpression of the trypanosomatid-exclusive TcRBP19 RNA-binding protein affects cellular infection by Trypanosoma cruzi. Mem Inst Oswaldo Cruz 107:1076-1079., 2013Pérez-Díaz L, Pastro L, Smircich P, Dallagiovanna B and Garat B (2013) Evidence for a negative feedback control mediated by the 3’ untranslated region assuring the low expression level of the RNA binding protein TcRBP19 in T. cruzi epimastigotes. Biochem Biophys Res Commun 436:295-299.) |
RRM |
DRBD4/PTB2 |
Involved regulation of splicing |
De Gaudenzi et al., (2016)De Gaudenzi JG, Jäger AV, Izcovich R and Campo VAO (2016) Insights into the regulation of mRNA processing of polycistronic transcripts mediated by DRBD4/PTB2, a trypanosome homolog of the polypyrimidine tract-binding protein. J Eukaryot Microbiol 63440-452.
|
RRM |
PABP1 |
Involved in translation |
Batista et al. (1994)Batista JA, Teixeira SM, Donelson JE, Kirchhoff LV and de Sá CM (1994) Characterization of a Trypanosoma cruzi poly(A)-binding protein and its genes. Mol Biochem Parasitol 67:301-312.
|
RRM |