Actin, aortic smooth muscle |
P62736 |
1.56782 |
Highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
ACTA2 |
Cytoplasm, cytoskeleton. |
Actin, gamma-enteric smooth muscle |
P63267 |
1.47153 |
Highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
ACTG2 |
Cytoplasm, cytoskeleton. |
Actin, cytoplasmic 2 |
P63261 |
1.84219 |
Highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
ACTG1 |
Cytoplasm, cytoskeleton. |
Tropomyosin beta chain |
P07951 |
1.29052 |
Binds to actin filaments in muscle regulates vertebrate striated muscle contraction; regulates smooth muscle contraction. |
TPM2 |
Cytoplasm, cytoskeleton. |
Transgelin |
Q01995 |
-1.23158 |
Involves in calcium interactions and contractile properties of the cell that may contribute to replicative senescence |
TAGLN |
Cytoplasm. |
Vimentin |
P08670 |
2.15428 |
Class-III intermediate filaments found in various non-epithelial cells, and is attached to the nucleus, endoplasmic reticulum, and mitochondria. |
VIM |
Cell membrane, cytoplasm. cytoskeleton, intermediate filament, membrane, nucleus. |
Annexin A2 |
P07355 |
1.51842 |
May be involves in heat-stress response. |
ANXA2 |
Basement membrane, extracellular matrix, secreted. |
Annexin A5 |
P08758 |
1.36364 |
Involves in the blood coagulation cascade. |
ANXA5 |
Cytosol, extracellular region or secreted, plasma membrane. |
Gelsolin |
P06396 |
1.20617 |
Prevents monomer exchange (end-blocking or capping), promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. |
GSN |
Amyloid, cytoplasm, cytoskeleton, secreted. |
Cofilin-1 |
P23528 |
1.35534 |
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity, regulates cell morphology and cytoskeletal organization in epithelial cells |
CFL1 |
Cell membrane, cell projection, cytoplasm, cytoskeleton, membrane, nucleus. |
LIM and SH3 domain protein 1 |
Q14847 |
-1.68030 |
Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities, regulates actin-associated ion transport activities. |
LASP1 |
Cytoplasm, cytoskeleton. |
Sorbin and SH3 domain-containing protein 2 |
O94875 |
-1.41926 |
Adapter protein that plays a role in the assembling of signaling complexes; may participates in the regulation of pancreatic cell adhesion; isoform 6 increases water and sodium absorption in the intestine and gall-bladder. |
SORBS2 |
Cell junction, cell membrane, cell projection, cytoplasm, membrane. |
Keratin, type I cytoskeletal 9 |
P35527 |
1.20084 |
May involves in the mature palmar and plantar skin tissue. |
KRT9 |
Intermediate filament, keratin. |
Prelamin-A/C |
P02545 |
-1.30005 |
Participates in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. |
LMNA |
Intermediate filament, nucleus. |
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase |
Q13011 |
-1.45960 |
Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. |
ECH1 |
Mitochondrion, peroxisome. |
Galactokinase |
P51570 |
1.86176 |
Catalyzes the transfer of a phosphate from ATP to alpha-D-galactose and participates in the first committed step in the catabolism of galactose. |
GALK1 |
Cytosol, extracellular region or secreted, extracellular exosome Source. |
Pyruvate kinase PKM |
P14618 |
1.20084 |
Generates ATP; regulates transcription; tumor cell proliferation and survival. |
PKM |
Nucleus, cytoplasm and cytosol. |
Protein AMBP |
P02760 |
1.42851 |
1. Alpha-1-microglobulin: removes and protects against harmful oxidants and repairs macromolecules in intra- and extra-vascular spaces; intravascularly, plays a regulatory role in red cell homeostasis. 2. Inter-alpha-trypsin inhibitor light chain: extracellular space remodeling and cell adhesion. |
AMBP |
Nucleus, extracellular region or secreted, plasma membrane, cell membrane, cytoplasm and cytosol, mitochondrion, peripheral membrane protein. |
Glutathione S-transferase P |
P09211 |
1.46583 |
Involves in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). |
GSTP1 |
Cytoplasm, mitochondrion, nucleus. |
Fibrinogen beta chain |
P02675 |
-1.36779 |
Fibrin has a major function in hemostasis as one of the primary components of blood clots; involved in the early stages of wound repair; associated with infection and facilitate the antibacterial immune response. |
FGB |
Secreted. |
Biglycan |
P21810 |
-1.29570 |
May be involved in collagen fiber assembly. |
BGN |
Extracellular matrix, secreted. |
Heat shock protein beta-1 |
P04792 |
1.34520 |
A molecular chaperone probably maintaining denatured proteins in a folding-competent state, and involves in stress resistance and actin organization. |
HSPB1 |
Cytoplasm, cytoskeleton, nucleus. |
Polymerase I and transcript release factor |
Q6NZI2 |
1.75672 |
Involves in caveolae formation and organization in all tissues. |
CAVIN1 |
Cell membrane, cytoplasm, endoplasmic reticulum, microsome, mitochondrion, nucleus. |
Ras suppressor protein 1 |
Q15404 |
-2.15990 |
Potentially plays a role in the Ras signal transduction pathway. |
RSU1 |
Cytosol, extracellular region or secreted, etc. |