1 |
ESR1 |
total newborn, newborn alive |
14217032 |
14604906 |
Rothschild et al., 1996Rothschild M, Jacobson C, Vaske D, Tuggle C, Wang L, Short T, Eckardt G, Sasaki S, Vincent A, McLaren D et al. (1996) The estrogen receptor locus is associated with a major gene influencing litter size in pigs. Proc Natl Acad Sci U S A 93:201–205.
|
1 |
VPS13A |
maintenance of thermostatic status, blood circulation |
230069339 |
230331343 |
Groenen, 2016Groenen MAM (2016) A decade of pig genome sequencing: A window on pig domestication and evolution. Genet Sel Evol 48:23.
|
1 |
NR6A1 |
body size |
265320597 |
265570941 |
Groenen, 2016Groenen MAM (2016) A decade of pig genome sequencing: A window on pig domestication and evolution. Genet Sel Evol 48:23.
|
2 |
FSHB |
total newborn, newborn alive |
30395769 |
30399282 |
Zhao et al., 1998Zhao Y,Li N,Xiao L,Cao G,Chen Y,Zhang S,Chen Y,Wu C, Zhang J,Sun S et al. (1998). FSHBsubunitgeneis associated with majorgenecontrolling litter size in commercial pig breeds. Sci China C Life Sci 1(6):664-668.
Domestic Animal Diversity Information System (DAD-IS), http://dad.fao.org/. http://dad.fao.org/...
|
3 |
EIF2AK3 |
gene overlaps with QTLs for osteochondrosis score and feet and leg conformation |
57423894 |
57506247 |
Laenoi et al., 2011Laenoi W, Uddin MJ, Cinar MU, Grosse-Brinkhaus C, Tesfaye D, Jonas E, Scholz AM, Tholen E, Looft C, Wimmers K et al. (2011) Quantitative trait loci analysis for leg weakness related traits in a Duroc Pietrain crossbred population. Genet Sel Evol 43:13.
|
3 |
AZGP1 |
adaptation to environment |
7867521 |
7874857 |
Beeckmann et al., 2003Beeckmann P, Schroffel J, Moser G, Bartenschlager H, Reiner G and Geldermann H (2003) Linkage and QTL mapping for Sus scrofa chromosome 3. J Anim Breed Genet 120:20–27.; Ma et al., 2009Ma J, Qi W, Ren D, Duan Y, Qiao R, Guo Y, Yang Z, Li L, Milan D, Ren J and Huang L (2009) A genome scan for quantitative trait loci affecting three ear traits in a White Duroc x Chinese Erhualian resource population. Anim Genet 40:463–467.; Harmegnies et al., 2006Harmegnies N, Davin F, De Smet S, Buys N, Georges M and Coppieters W (2006) Results of a whole-genome quantitative trait locus scan for growth, carcass composition and meat quality in a porcine four-way cross. Anim Genet 37:543–553.
|
4 |
PLAG1 |
body size |
75646585 |
75696718 |
Rubin et al., 2012Rubin CJ, Megens HJ, Barrio AM, Maqbool K, Sayyab S, Schwochow D, Wang C, Carlborg O, Jern P, Jørgensen CB et al. (2012) Strong signatures of selection in the domestic pig genome. Proc Natl Acad Sci U S A 109:19529–19536.
|
6 |
IL12RB2 |
immune related gene |
145210251 |
145292399 |
Koch et al., 2012Koch MA, Thomas KR, Perdue NR, Smigiel KS, Srivastava S and Campbell DJ (2012) T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2. Immunity 37:501–510.; Herrero-Medrano et al., 2014Herrero-Medrano JM, Megens HJ, Groenen M, Bosse M, Pérez-Enciso M and Crooijmans R (2014) Whole-genome sequence analysis reveals differences in population management and selection of European low-input pig breeds. BMC Genomics 15:601.
|
6 |
FUT1 |
resistance to disease |
54077431 |
54080475 |
Meijerink et al., 1997Meijerink E, Fries R, Vögeli P, Masabanda J, Wigger G, Stricker C, Neuenschwander S, Bertschinger HU and Stranzinger G (1997) Two α(1,2) fucosyltransferase genes on porcine Chromosome 6q11 are closely linked to the blood group inhibitor (S) and Escherichia coli F18 receptor (ECF18R) loci. Mamm Genome 8:736–741., 2000Meijerink E, Neuenschwander S, Fries R, Dinter A, Bertschinger GS and Vögeli P (2000) A DNA polymorphism influencing α(1,2)fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion. Immunogenetics 52:129–136.; Bao et al., 2012Bao WB, Ye L, Zi C, Su XM, Pan Zy, Zhu J, Zhu GQ, Huang XG and Wu SL (2012) Study on the age-dependent tissue expression of FUT1 gene in porcine and its relationship to E. coli F18 receptor. Gene 497:336-339.; Zhang et al., 2015Zhang Y, Wang M, Yu XQ, Ye CR and Zhu JG (2015) Analysis of polymorphisms in the FUT1 and TAP1 genes and their influence on immune performance in Pudong White pigs. Genet Mol Res 14:17193-17203.; Fernández et al., 2017Fernández AI, Muñoz M, García F, Núñez Y, Geracci C, Crovetti A, García-Casco J, Alves E, Skrlep M, Riquet J et al. (2017) Distribution of polymorphisms in major and candidate genes for productive and domestication-related traits in European local pig breeds. 36th International Society for Animal Genetics Conference, Dublin.
|
8 |
GNRHR |
Ovulation rate |
65470206 |
65488900 |
Jiang et al., 2001Jiang Z, Gibson JP, Archibald AL and Haley CS (2001) The porcine gonadotropin-releasing hormone receptor gene (GNRHR): Genomic organization, polymorphisms, and association with the number of corpora lutea. Genome 44:7-12.
|
8 |
LCORL |
body size |
12806878 |
12969370 |
Rubin et al., 2012Rubin CJ, Megens HJ, Barrio AM, Maqbool K, Sayyab S, Schwochow D, Wang C, Carlborg O, Jern P, Jørgensen CB et al. (2012) Strong signatures of selection in the domestic pig genome. Proc Natl Acad Sci U S A 109:19529–19536.
|
9 |
AHR |
litter size |
86511866 |
86555950 |
Bosse et al., 2014Bosse M, Megens HJ, Frantz LAF, Madsen O, Larson G, Paudel Y, Duijvensteijn N, Harlizius B, Hagemeijer Y, Crooijmans RP et al. (2014) Genomic analysis reveals selection for Asian genes in European pigs following human-mediated introgression. Nat Comm 5:4392.
|
12 |
PPP1R1B |
candidate genes affecting behaviour |
22681244 |
22690978 |
Groenen, 2016Groenen MAM (2016) A decade of pig genome sequencing: A window on pig domestication and evolution. Genet Sel Evol 48:23.
|
13 |
STAB1 |
immune related gene, defence against bacterial infection |
34630448 |
34659371 |
Herrero-Medrano et al., 2014Herrero-Medrano JM, Megens HJ, Groenen M, Bosse M, Pérez-Enciso M and Crooijmans R (2014) Whole-genome sequence analysis reveals differences in population management and selection of European low-input pig breeds. BMC Genomics 15:601.; Kzhyshkowska, 2010Kzhyshkowska J (2010) Multifunctional receptor stabilin-1 in homeostasis and disease. Sci World J 10:2039–2053.
|
13 |
GPR149 |
potential effect on fertility, prolificacy |
94356371 |
94419917 |
Choi et al., 2015Choi JW, Chung WH, Lee KT, Cho ES, Lee SW, Choi BH, Lee SH, Lim W, Lee YG, Hong JK et al. (2015) Whole-genome resequencing analyses of five pig breeds, including Korean wild and native, and three European origin breeds. DNA Res 22:259–267.
|
13 |
CLDN1 |
potential effect on fertility |
127714857 |
127730628 |
Choi et al., 2015Choi JW, Chung WH, Lee KT, Cho ES, Lee SW, Choi BH, Lee SH, Lim W, Lee YG, Hong JK et al. (2015) Whole-genome resequencing analyses of five pig breeds, including Korean wild and native, and three European origin breeds. DNA Res 22:259–267.
|
14 |
RBP4 |
total newborn, newborn alive |
105037360 |
105044552 |
Rothschild et al., 2000Rothschild M, Messer L, Day A, Wales R, Short T, Southwood O and Plastow G (2000) Investigation of the retinol-binding protein 4 (RBP4) gene as a candidate gene for increased litter size in pigs. Mamm Genome 11:75–77.
|
14 |
JMJD1C |
potential effect on fertility |
66640845 |
66966911 |
Choi et al., 2015Choi JW, Chung WH, Lee KT, Cho ES, Lee SW, Choi BH, Lee SH, Lim W, Lee YG, Hong JK et al. (2015) Whole-genome resequencing analyses of five pig breeds, including Korean wild and native, and three European origin breeds. DNA Res 22:259–267.
|
15 |
DCAF17 |
maintenance of thermostatic status, hair growth |
77564629 |
77603913 |
Groenen et al., 2016Groenen MAM (2016) A decade of pig genome sequencing: A window on pig domestication and evolution. Genet Sel Evol 48:23.
|
16 |
PRLR |
involved in several reproductive traits, including litter size |
20637568 |
20655881 |
Vincent et al., 1998Vincent AL, Tuggle CK, Rothschild MF, Evans G, Short TH, Southwood OI and Plastow GS (1998) The prolactin receptor gene is associated with increased litter size in pigs. Swine Research Report, 1997.; van Rens et al., 2003van Rens BTTM, Evans GJ and Van Der Lende T (2003) Components of litter size in gilts with different prolactin receptor genotypes. Theriogenology 59:915–926.; Tomás et al., 2006Tomás A, Casellas J, Ramírez O, Muñoz G, Noguera J and Sánchez A (2006) High amino acid variation in the intracellular domain of the pig prolactin receptor (PRLR) and its relation to ovulation rate and piglet survival traits. J Anim Sci 84:1991–1998.
|
18 |
TAS2R40 |
adaptation to specific dietary repertoires and environment |
7024418 |
7027197 |
Dong et al., 2009Dong D, Jones G and Zhang S (2009) Dynamic evolution of bitter taste receptor genes in vertebrates. BMC Evol Biol 9:12.; Fischer et al.,2005Fischer A, Gilad Y, Man O and Pääbo S (2005) Evolution of bitter taste receptors in humans and apes. Mol Biol Evol 22:432–436.,Ribani et al., 2017Ribani A, Bertolini F, Schiavo G, Scotti E, Utzeri VJ, Dall’Olio S, Trevisi P, Bosi P and Fontanesi L (2017) Next generation semiconductor based sequencing of bitter taste receptor genes in different pig populations and association analysis using a selective DNA pool-seq approach. Anim Genet 48:97–102.
|