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Short Report • J. Braz. Chem. Soc. 16 (3a) • June 2005 • https://doi.org/10.1590/S0103-50532005000300026   copy

A concise total synthesis of (R)-fluoxetine, a potent and selective serotonin reuptake inhibitor

Authorship SCIMAGO INSTITUTIONS RANKINGS

(R)-Fluoxetine, potent and selective serotonin reuptake inhibitor, has been synthesized in six steps, 50% overall yield and 99% ee from benzaldehyde via catalytic asymmetric allylation with Maruoka's catalyst.

fluoxetine; serotonin reuptake inhibitor; catalytic asymmetric allylation

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