8-O-4'-Neolignans from flower buds of Magnolia fargesii and their biological activities

Abstract

Three new 8-O-4'-neolignans, fargesiphenols A-C, together with six known neolignans, were isolated from the flower buds of Magnolia fargesii. The structures were elucidated by spectroscopic methods, including extensive 1D and 2D-NMR techniques. Compounds were also tested for their anti-HIV-1 activities and cytotoxicities.

Magnolia fargesii; 8-O-4'-neolignans; anti-HIV-1 activity; cytotoxicity