Background and aims: Gastric carcinoma (GC) is highly prevalent in our population. There are few studies about GC characteristics in Brazil, therefore, we report our data in a series of GC examined in a 10 years period. Material and methods: Surgical specimens from 289 patients submitted to gastrectomy were examined according to a standardized protocol. Results: Most of the tumors (n = 170, 59%) had distal localization, 230 were advanced, mainly Borrmann III type, and 36 cases were early tumors, mainly type II; 115 cases (40%) were expansive and 122 (42%) were infiltrative according to Ming's; 178 cases (62%) were intestinal-type (IGC), 61 (21%) were diffuse-type (DGC) and 50 cases (17%) were mixed type. Among IGC, 116 patients were men (65%) and 61 (35%) were women (1,9:1), mean age of 67.1± 11.8 years; among DGC 36 patients were men (59%) and 25 (41%) were women (1.4:1), mean age 59.3 ± 14.2 years, significantly lower than in IGC (p = 0.001). IGC were predominantly Borrmann types I or II, whereas DGC were commonly Borrmann types III or IV (p = 0.004). DGC were in more advanced stages than IGC (p = 0.02). Nerve invasion was more frequent in DGC cases (p < 10-7). Chronic atrophic gastritis and intestinal metaplasia were quite common among IGC (81% and 67%) and DGC (77% and 59%). Conclusions: Our data are similar to those reported from medium and high GC risk populations. Intestinal-type distally located GC are predominant and most of the cases are advanced tumors without any possibility of curative treatment.
Gastric carcinoma; Pathology; Diagnosis; Adenocarcinoma
