We report the case of a 23 year old man who believed he emitted an unpleasant odor from perspiration which he’s believed bothered other people. He was treated with amisulpride in combination with cognitive-behavioral therapy (CBT), and there was marked improvement in the clinical status. Aspects related to the clinical manifestations and nosology of olfactory reference syndrome (ORS) and treatment were discussed. It was noted that behavioral experiments involving exposure with challenge to the delusional beliefs may be useful in the treatment of this disorder, and antipsychotics, particularly amisulpride may be a good alternative to the serotonin reuptake inhibitors (SRIs) in the treatment of ORS.
Exposure; olfactory reference syndrome; cognitive behavior therapy; somatoform disorders