Abstract
Objective:
This study aimed to describe the effect of prophylactic phototherapy in the treatment of infants with Neonatal Hemolytic Disease.
Method:
A retrospective cohort study was carried out with 199 RhD-positive infants, born to RhD-negative mothers, alloimmunized for RhD antigen, between January 2009 and December 2018.
Results:
The incidence of exchange transfusions in the study population was 9.5%, with a mean maximum bilirubin value of 11.3 mg % (± 4.3mg %). Bilirubin’s maximum peak was achieved with a mean of 119.2 life hours (± 70.6h).
Conclusions:
The low incidence of exchange transfusion, the extended maximum bilirubin peak for later ages, and the low mean of the maximum bilirubin values may indicate a positive effect of prophylactic phototherapy in the treatment of this disease. Further studies must be carried out to confirm these findings.
KEYWORDS
Hemolytic disease of the newborn; Rh isoimmunization; Phototherapy; Neonatal hyperbilirubinemia
Thumbnail
Thumbnail
