Atividade quimioprofilática de sabonetes contendo óleo essencial de frutos de Pterodon pubescens na esquistossomose mansoni

Chemoprophylactic activity of soaps containing essential oil of Pterodon pubescens fruits in Schistosomiasis mansoni

D. Santos Filho S. J. Sarti N. Katz N. Araújo P. A. Rocha Filho J. E. Abreu M. E. Bortolin Sobre os autores

Resumo

It has been studied the chemoprophylactic action on experimental schistosomiasis of the essential oil from Pterodon pubescens "sucupira branca" as an additive through different formulations, in toilet soap. Immediately or 24 hours later, groups of mice were exposed by tail method to Schistosoma mansoni cercariae. After 45 days of the exposition, the protective action of these soaps were evaluated. The results showed different levels of protection, ranging from 29.0 to 100.0%. Further studies are on going with the most promising formulations.


ABSTRACT

Atividade quimioprofilática de sabonetes contendo óleo essencial de frutos de Pterodon pubescens na esquistossomose mansoni

D. Santos Filho1

S. J. Sarti1

N. Katz2

N. Araújo2

P. A. Rocha Filho1

J. E. Abreu1

M. E. Bortolin1

USP, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Ribeirão Preto, Brasil

FIOCRUZ, Centro de Pesquisas René Rachou, Belo Horizonte, Brasil

It has been studied the chemoprophylactic action on experimental schistosomiasis of the essential oil from Pterodon pubescens "sucupira branca" as an additive through different formulations, in toilet soap. Immediately or 24 hours later, groups of mice were exposed by tail method to Schistosoma mansoni cercariae. After 45 days of the exposition, the protective action of these soaps were evaluated. The results showed different levels of protection, ranging from 29.0 to 100.0%. Further studies are on going with the most promising formulations.

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Datas de Publicação

  • Publicação nesta coleção
    26 Jun 2009
  • Data do Fascículo
    1987
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