Anti-embryonation immunity in murine schistosomiasis japonica (Philippines)

Abstract

The hypothesis that granuloma modulation and disease abatement in chronic infection with Schistosoma japonicum could be ascribed to antibody-mediated effects on egg maturation and egg viability, arose from studies performed with mice in the Philippines. This novel hypothesis has not yet been integrated into the schistosomiasis literature despite being formulated more than a decade ago. One reason for this is that the phenomenon might be confined to S. japonicum, even S. japonicum (Philippines).

schistosomiasis japonica; granuloma modulation; COP test; egg antigens; egg embryonation; egg viability


ABSTRACT

Anti-embryonation immunity in murine schistosomiasis japonica (Philippines)

G. F. Mitchell1

E. G. Garcia2

K. M. Davern3

W. U. Tiu4

CSL Limited, Parkville, Australia

University of the Philippines Manila, College of Public Health, Manila, Philippines

The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia

University of the Philippines Manila, College of Public Health, Philippines

The hypothesis that granuloma modulation and disease abatement in chronic infection with Schistosoma japonicum could be ascribed to antibody-mediated effects on egg maturation and egg viability, arose from studies performed with mice in the Philippines. This novel hypothesis has not yet been integrated into the schistosomiasis literature despite being formulated more than a decade ago. One reason for this is that the phenomenon might be confined to S. japonicum, even S. japonicum (Philippines).

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Publication Dates

  • Publication in this collection
    01 June 2009
  • Date of issue
    Mar 1995
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