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• Mem. Inst. Oswaldo Cruz 89 (suppl 2) • 1994 • https://doi.org/10.1590/S0074-02761994000600004   copy

Transmission blocking immunity as observed in a feeder system and serological reactivity to Pfs 48/45 and Pfs230 in field sera

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Monoclonal antibodies (mAbs) and human sera from gametocyte carriers were applied in the bio-assay to test for their transmission-blocking capacity. Competition ELISA's have been developed for the detection of natural transmission blocking antibodies. Approximately 55 of the sera blocking in the bio-assay gave positive results in these competition ELISA's.

Plasmodium falciparum; transmission; natural antibodies; competition ELISA's

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