Through revision of the literature, data are presented about vitamin D metabolism and the toxicological, clinical, biochemical, macro and microscopic, ultrastructural, immunhistochemical and radiographic aspects in animals of different species poisoned natural and experimentally by the vitamin. We aimed to show the existence of many lacunae in the knowledge of physiological and pathological tissue mineralization, especially regarding the hormonal metabolism of vitamin D, and to alert for risk of the poisoning.
Hypervitaminosis D; vitamin D poisoning; animals; pathology
