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Lethal midline granuloma: clinical management of three cases

PURPOSE: We report three cases of LMG followed at Disciplina de Hematologia e Hemoterapia from Unifesp-EPM with good response to conventional treatment and favorable outcome. METHODS: After histological and histochemical analyses, patientes were treatd with combined chemo-and radiotherapy with favorable evolution. RESULTS: Currently they present clinical complete remission, with mean survival of 45 months. CONCLUSION: Despite of our small experience, we believe that combined aggressive therapy is extremely important for further favorable evolution in this type of lymphoma.

Lethal midline granuloma; Non-Hodgkin lymphoma; Treatment


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