Rustin et al., 198477 Rustin GJ, Booth M, Dent J, Salt S, Rustin F, Bagshawe KD. Pregnancy after cytotoxic chemotherapy for gestational trophoblastic tumours. Br Med J (Clin Res Ed). 1984; 288(6411):103-6.
|
|
245 |
|
368 |
|
273 (74.1) |
|
8 (2.1) |
|
55 (15) |
|
- |
|
5 (1.3) |
|
2 (0.5)
|
Song et al., 198888 Song HZ, Wu PC, Wang YE, Yang XY, Dong SY. Pregnancy outcomes after successful chemotherapy for choriocarcinoma and invasive mole: long-term follow-up. Am J Obstet Gynecol. 1988; 158(3 Pt 1):538-45.
|
|
205 |
|
355 |
|
279 (78.6) |
|
5 (1.4) |
|
28 (8) |
|
- |
|
20 (6.7) |
|
3 (1)
|
Kim et al., 199899 Kim JH, Park DC, Bae SN, Namkoong SE, Kim SJ. Subsequent reproductive experience after treatment for gestational trophoblastic disease. Gynecol Oncol. 1998; 71(1):108-12.
|
|
517 |
|
115 |
|
89 (77.4) |
|
1 (0.9) |
|
17 (15) |
|
5 (4.3) |
|
3 (2.6) |
|
3 (3.2)
|
Woolas et al., 199866 Woolas RP, Bower M, Newlands ES, Seckl M, Short D, Holden L. Influence of chemotherapy for gestational trophoblastic disease on subsequent pregnancy outcome. Br J Obstet Gynaecol. 1998; 105(9):1032-5.
|
|
680 |
|
1,313 |
|
1,000 (76.2) |
|
19 (1.4) |
|
190 (14.5) |
|
18 (1.4) |
|
- |
|
18 (1.7)
|
Tuncer et al., 19991010 Tuncer ZS, Bernstein MR, Goldstein DP, Berkowitz RS. Outcome of pregnancies occurring before completion of human chorionic gonadotropin follow-up in patients with persistent gestational trophoblastic tumor. Gynecol Oncol. 1999; 73(3):345-7.
|
|
43 |
|
29 |
|
22 (75.9) |
|
- |
|
3 (10.3) |
|
1 (3.4) |
|
3 (10.3) |
|
1 (4.1)
|
Amr et al., 19991111 Amr MF. Return of fertility after successful chemotherapy treatment of gestational trophoblastic tumors. Int J Fertil Womens Med. 1999; 44(3):146-9.
|
|
42 |
|
120 |
|
94 (78.3) |
|
3 (2.5) |
|
8 (6.8) |
|
- |
|
15 (12.5) |
|
- |
Lan et al., 20011212 Lan Z, Hongzhao S, Xiuyu Y, Yang X. Pregnancy outcomes of patients who conceived within 1 year after chemotherapy for gestational trophoblastic tumor: a clinical report of 22 patients. Gynecol Oncol. 2001; 83(1):146-8.
|
|
22 |
|
22 |
|
9 (40.9) |
|
1 (4.5) |
|
1 (4.5) |
|
1 (4.5) |
|
1 (4.5) |
|
- |
Blagden et al., 20021414 Blagden SP, Foskett MA, Fisher RA, Short D, Fuller S, Newlands ES, et al. The effect of early pregnancy following chemotherapy on disease relapse and foetal outcome in women treated for gestational trophoblastic tumours. Br J Cancer. 2002; 86(1):26-30.
|
|
1,532 |
|
230 |
|
164 (71) |
|
2 (1) |
|
26 (11) |
|
3 (1.3) |
|
- |
|
3 (1.3)
|
Garner et al., 20021515 Garner E, Goldstein DP, Berkowitz RS, Wenzel L. Psychosocial and reproductive outcomes of gestational trophoblastic diseases. Best Pract Res Clin Obstet Gynaecol. 2003; 17(6):959-68.
|
|
- |
|
581 |
|
393 (67.6) |
|
9(1.5) |
|
106 (18) |
|
8 (1.4) |
|
35 (6) |
|
10 (2.3)
|
Matsui et al., 20021313 Matsui H, Iitsuka Y, Suzuka K, Yamazawa K, Seki K, Sekiya S. Outcome of subsequent pregnancy after treatment for persistent gestational trophoblastic tumour. Hum Reprod. 2002; 17(2):469-72.
|
|
129 |
|
243 |
|
169 (69.5) |
|
2 (0.8) |
|
27 (11.1) |
|
5 (2.1) |
|
5 (2.1) |
|
- |
Lok et al., 20031616 Lok CA, van der Houwen C, ten Kate-Booij MJ, van Eijkeren MA, Ansink AC. Pregnancy after EMA/CO for gestational trophoblastic disease: a report from The Netherlands. BJOG. 2003; 110(6):560-6.
|
|
50 |
|
21 |
|
16 (76) |
|
- |
|
2 (9) |
|
- |
|
2 (9) |
|
2 (11)
|
Matsui et al., 20041717 Matsui H, Iitsuka Y, Suzuka K, Yamazawa K, Tanaka N, Mitsuhashi A, et al. Early pregnancy outcomes after chemotherapy for gestational trophoblastic tumor. J Reprod Med. 2004; 49(7):531-4.
|
|
137 |
|
258 |
|
180 (69.8) |
|
3 (1.2) |
|
29 (11.2) |
|
5 (1.9) |
|
5 (1.9) |
|
- |
Goto et al., 20041818 Goto S, Ino K, Mitsui T, Kikkawa F, Suzuki T, Nomura S, et al. Survival rates of patients with choriocarcinoma treated with chemotherapy without hysterectomy: effects of anticancer agents on subsequent births. Gynecol Oncol. 2004; 93(2):529-35.
|
|
50 |
|
43 |
|
34(79) |
|
0 |
|
4 (9.3) |
|
0 |
|
0 |
|
3 (8.8)
|
Garrett et al., 20081919 Garrett LA, Garner EI, Feltmate CM, Goldstein DP, Berkowitz RS. Subsequent pregnancy outcomes in patients with molar pregnancy and persistent gestational trophoblastic neoplasia. J Reprod Med. 2008; 53(7):481-6.
|
|
- |
|
631 |
|
422 (66.9) |
|
9 (1.4) |
|
7 (1.1) |
|
9 (1.4) |
|
42 (6.7) |
|
10 (2.1)
|
Braga et al., 20092020 Braga A, Maestá I, Michelin OC, Delmanto LR, Consonni M, Rudge MV, et al. Maternal and perinatal outcomes of first pregnancy after chemotherapy for gestational trophoblastic neoplasia in Brazilian women. Gynecol Oncol. 2009; 112(3):568-71.
|
|
- |
|
252 |
|
172 (68.2) |
|
2 (0.8) |
|
42 (16) |
|
7 (2.8) |
|
6 (2.4) |
|
6 (2.4)
|
Williams et al., 20142121 Williams J, Short D, Dayal L, Strickland S, Harvey R, Tin T, et al. Effect of early pregnancy following chemotherapy on disease relapse and fetal outcome in women treated for gestational trophoblastic neoplasia. J Reprod Med. 2014; 59(5-6):248-54.
|
|
1,204 |
|
255 |
|
174 (68.2) |
|
2 (0.8) |
|
34 (13.4) |
|
3 (1.4) |
|
14 (5.4) |
|
- |
Total
|
|
|
|
4,836
|
|
3,490 (72)
|
|
66 (1.4)
|
|
579 (12)
|
|
65 (1.6)
|
|
156 (4.7)
|
|
89 (2.3)
|