| Ototoxic medication utilized in pediatric oncologic treatment: systematic review |
Caldas et al., 201828
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Find which ototoxic medications utilized to treat lung cancer of children are more investigated in the literature, the impact of these drugs on the auditory system and methods to identify damages |
Ototoxic medications for cancer treatment have highlighted the importance of monitoring hearing in children because knowing the effects and identify the suitable tests can minimize damages and improve the quality of life. Cisplatin is known by its ototoxicity while carboplatin, though less toxic, can also cause neurosensorial hearing loss, especially in younger children. Aminoglycosides and radiotherapy contribute to ototoxicity with hearing impacts that can appear during and after the treatment, justifying regular follow-up. Liminal tone audiometry is the golden standard test but otoacoustic emissions are more viable and sensitive to monitor hearing of children exposed to ototoxic drugs. It is crucial to perform periodic audiologic evaluations to detect late complications and guide families and educators on possible damages and adjustments as auditory prosthetics |
| Evaluation of the handgrip strength and quality of life of children with cancer submitted to chemotherapy with vincristine |
Costa et al., 201829
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Evaluate the handgrip strength and quality of life of children and adolescents with cancer submitted to vincristine-based chemotherapy |
Acute lymphoblastic leukemia was the most prevalent diagnosis, unlike other studies that indicate higher incidence in boys. Significant decline of muscle strength measured by handgrip strength after starting chemotherapy, corroborating the importance of evaluating the integrity of upper limbs and global strength. Vincristine-based chemotherapy caused peripheral neuropathy, muscle weakness and decline of the quality of life requiring supervised physiotherapy. Children and their parents perceived quality of life differently, usually parents were most anxious and worried than their children. Similar studies are recommended to improve physical treatment and social aspects of these patients |
| Physical activity and cancer treatment of children |
Freguglia et al., 201630
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Physical activities during childhood cancer treatment described by the studies found on the database CAPES (Journals Portal) with the following key-words: Cancer, Children, Physical Activity e Chemotherapy; text analysis and drafting of the thematic units |
The authors highlighted the evidence-based benefits of physical activity on the quality of life of patients in cancer treatment although the different number of patients and ages made results difficult to be proven. Physical activity in hospitals needs to be more explored by the literature because results vary widely, only two studies suggested that the consequences caused neither benefits or harms. Comparison among studies were limited due to different ages, types of cancer and approaches, but there are indications that physical activity can benefit patients without causing any harm |
| Evaluation of the quality of life of patients with onco-hematologic diseases in chemotherapy |
Gomes et al., 201831
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Evaluate the quality of life of patients with onco-hematologic diseases in chemotherapy |
Global health evaluation of cancer patients revealed poor quality of life mainly because of low scores of emotional function, with depression, concerns and nervousness. Fatigue, insomnia and loss of appetite were the main symptoms reported that negatively impact physical, cognitive, social and emotional functions. These symptoms exacerbated by chemotherapy side effects highlight the necessity of nursing interventions to minimize suffering as psychological support, stimulate good feeding and physical exercises. Actions are meant to improve the quality-of-life of patients during and after the treatment |
| Evaluation of computer-generated guidelines to caretakers of pediatric patients submitted to chemotherapy |
Lopes and Shmeil, 201632
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Comparison of guidelines created by the Support System to Clinical Conduct – Oncologic Care and Health with Chemotherapy Drugs with non-technological generated guidelines for caretakers of children in chemotherapy treatment |
Analysis of the profile of caretakers and nurses involved with children in chemotherapy indicated that women predominate with similar difficulties regardless of the time caring for these children. Difficulties were not related to education. Nurses age, sex and education did not significantly impact the results but the utilization of the Support System increased the level of agreement and effectiveness of the guidelines provided to nurses and caretakers, improving the adherence to the treatment and quality of the care |
| The importance of playing for children in chemotherapy treatment and their experience |
Morais et al., 201833
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Understand the importance of playing for children in chemotherapy treatment |
The importance of playing for outpatient children and attention to care that value their potentialities. Playing is a viable tool allowing nurses to understand its importance and ensure its implementation within this scenario. It helps to reduce inactivity and suffering, turning time into something useful and satisfactory. Ludic activities facilitate the formation of affectionate bonds among the nurses and children, favoring individualized care. Despite the difficulties, children see chemotherapy treatment ambivalently associated with pain but hope of cure too |
| Childhood cancer: profile of the patients attended to at a High Complexity Cancer Unit (Unacon) in Rio Branco – Acre, Brazil in 2017 |
Nascimento et al., 202034
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Describe the clinical and epidemiologic profile of children and adolescents attended to at a High Complexity Cancer Unit in 2017 |
Description of the clinical-epidemiological profile of children and adolescents, mostly males (60%), Brown color (70%) aged 1-3 years old (45%) treated at the High Complexity Cancer Unit in Rio Branco, Acre in 2017, whose families earned up to one minimum wage (60%). Half of the patients lived in the rural area. Acute lymphoid leukemia (ALL) was the most common cancer type (45%), predominantly treated with chemotherapy (95%). Main treatment side effects were alopecia (hair loss), pain, nausea, paleness and fever. The study highlights the importance of understanding these characteristics for improved humanization of healthcare for this population |
| Palliative care: prevalence of fatigue in pediatric patients |
Oliveira et al., 201735
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Evaluate fatigue and quality of life in pediatric cancer patients admitted to the ward in the perspective of palliative care |
Most of the participants were males with high incidence of childhood cancer, prevalence of fatigue and health-related quality of life closely associated with each study and populations. Children and adolescents and their parents reported nausea as a common and difficult symptom to control, even with antiemetics. Physical appearance, anxiety and communication were scored low, especially for parents who were more anxious than children. The results suggest that physical symptoms are perceived by children and parents alike but subjective issues are dissimilar, reflecting the emotional complexity of the chemotherapy treatment |
| Semantic validation of educational technology with caretakers of children and adolescents in chemotherapy treatment |
Silva et al., 202236
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Validate semantically an educational technology with the caretakers of children and adolescents in chemotherapy |
Technology was positive in regard to goals, clarity, language and motivation with high internal consistency (Cronbach alpha = 0.943). Females were predominant in the sample, reflecting the historical role of women as caretakers. Educational technology validated in digital animation media offers an interactive, effective and informative environment about chemotherapy treatment as preparation for therapeutic procedures and improved child care. The validation with the target-public is essential to ensure the relevance and dissemination of safe and reliable information |
| Nurse care in feeding children in chemotherapy: contributions of Collière |
Sueiro et al., 201937
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Understand nurse care after change of children's feeding habits due to chemotherapy in the perspective of Collière |
The results revealed that change of children's feeding habits due to chemotherapy are challenging for family and health professionals, including nurses. Nursing care should be continuous and rehabilitating to ensure food intake according to Collière. In this context, family should also be guided, further to articulation with the multiprofessional team, medication administration to relieve side effects, evaluation of pain and diet. Strategies include tactic approach to minimize mucositis, encourage the child with dialogue, games, plays and attractive and tasty frozen foods, respecting his/her space. Pursue of different strategies to create a relation of trust with the child and family, know his/her habits, preferences and tastes to meet their needs. A friendly hospital environment for children contributes to minimize the impact of hospitalization and improve the diet |