Abstract
Objective:
To assess the effects of postconditioning remote in ischemia-reperfusion injury in rat lungs.
Methods:
Wistar rats (n=24) divided into 3 groups: GA (I/R) n=8, GB (R-Po) n=8, CG (control) n=8, underwent ischemia for 30 minutes artery occlusion abdominal aorta, followed by reperfusion for 60 minutes. Resected lungs and performed histological analysis and classification of morphological findings in accordance with the degree of tissue injury. Statistical analysis of the mean rating of the degree of tissue injury.
Results:
GA (3.6), GB (1.3) and CG (1.0). (GA GB X P<0.05).
Conclusion:
The remote postconditioning was able to minimize the inflammatory lesion of the lung parenchyma of rats undergoing ischemia and reperfusion process.
Descriptors
Ischemia; Reperfusion; Ischemic Postconditioning; Lung Injury
