INTRODUCTION: E-learning, which refers to the use of Internet-related technologies to improve knowledge and learning, has emerged as a complementary form of education, bringing advantages such as increased accessibility to information, personalized learning, democratization of education and ease of update, distribution and standardization of the content. In this sense, this paper aims to present a tool, named ISE-SPL, whose purpose is the automatic generation of E-learning systems for medical education, making use of ISE systems (Interactive Spaced-Education) and concepts of Software Product Lines. METHODS: The tool consists of an innovative methodology for medical education that aims to assist professors of healthcare in their teaching through the use of educational technologies, all based on computing applied to healthcare (Informatics in Health). RESULTS: The tests performed to validate the ISE-SPL were divided into two stages: the first was made by using a software analysis tool similar to ISE-SPL, called S.P.L.O.T and the second was performed through usability questionnaires to healthcare professors who used ISE-SPL. CONCLUSION: Both tests showed positive results, allowing to conclude that ISE-SPL is an efficient tool for generation of E-learning software and useful for teachers in healthcare.
E-learning; Medical education; Software product lines