Different species of Baccharis belonging to the Trimera group are commonly named as carqueja and employed for their digestive and diuretic properties. Since the members of this group are alike, this work has aimed to study the macro and microscopical characters of Baccharis articulata, B. cylindrica, B. gaudichaudiana and B. trimera, in order to contribute for the drug analysis and to complement taxonomic knowledge for the Trimera group. These species are shrubs and have three-winged stem, except for B. articulata which possesses two wings. B. gaudichaudiana axis reveals ribs, B. articulata has oval contour and B. cylindrica and B. trimera stem is circular. In B. cylindrica and B. trimera, included phloem has been observed in older basal regions. Calcium oxalate crystals are seen in the four species, being styloid in B. articulata and B. cylindrica and prismatic in B. gaudichaudiana and B. trimera. The other microscopical features observed are similar.