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Primary acquired melanosis associated with recurrent corneal erosions

A case report of a 59 years old woman who has had ocular primary melanosis for four years, associated with episodes of corneal epithelial recurrent erosions. The patient underwent resection of the affected conjunctiva, superficial keratectomy and topical mitomicin C after the surgery. The pathologic examination confirmed the diagnosis of primary acquired melanosis, with mild to moderate nuclear atypia. One year after the treatment, she had only a small area of pigmented epithelium located in the lower corneal surface, showing no tendency to progression. She used lubricant ointment at night and did not have other epithelial erosions during the follow-up period.

Melanosis; Conjunctiva; Conjunctival neoplasms; Cornea; Mitomycin; Case reports


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