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Eosinophilic angiocentric fibrosis of the nasal cavity: case report and literature review

Eosinophilic angiocentric fibrosis (EAF) is a rare disease which affects the sinonasal tract. A few cases have been reported in the literature affecting the nose and maxillary sinus with even fewer cases in the subglottic area. The disease causes fibrotic proliferation of the nasal mucosa and nasal obstructive symptoms. We present the case of a male patient, 62 years old, with history of nasal obstruction for several years. The clinical examination showed septal enlargement and bilateral nasal obstruction. The patient was submitted to a septoplasty and the septal material was sent for histological examination, which showed the diagnosis of EAF. The aim of this report is to show a rare benign lesion (EAF) associated with nasal obstruction, its differential diagnosis with nasal granulomatosis and its histopathological and clinical features.

eosinophilic angiocentric fibrosis; nasal obstruction; nasal cavity


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