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Atypical evolution of juvenile nasopharyngeal angiofibroma

The authors report a 34-year-old patient presenting with an atypical juvenile angiofibroma. Symptoms had begun 14 years prior to diagnosis and the tumor occupied large extra and intracranial spaces. Following the last surgical intervention, the patient underwent radiotherapy and developed a nodule with benign characteristics on the face at the site of the incision. The mass was removed and recurred twice at the same site with the same histological characteristics. Recurrences occurred closer together and became progressively more hemorrhagic. Although histological characteristics remained benign, the clinical presentation suggested malignancy. The patient presented clinical complications and died six months after radiation therapy.

juvenile nasopharyngeal angiofibroma; intracranial extension; radiation therapy


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