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In vitro evaluation of Carapa guianensis Aubl. seed oil effects on larvae from gastrointestinal nematodes of goats and sheep

M.P.O Farias W.C Teixeira A.G Wanderley L.C Alves M.A.G Faustino About the authors

This study aimed to evaluate the in vitro action of Carapa guianensis (Andiroba) seed oil on the cultivation of larvae from gastrointestinal nematodes of goats and sheep. Five andiroba oil dilutions (100, 50, 30, 25, and 10%) were assayed, with three replicates per treatment, using Tween 80 as surfactant. Three control groups were formed: a negative control (distilled water), another negative control (distilled water + Tween 80) and a positive control (Doramectin). The activity of andiroba on the eggs from gastrointestinal nematodes was obtained by calculating larva reduction percentages per gram of feces. In goats, a highly effective reduction in the total number of larvae was detected for treatments 100, 50 and 30%, with null means for all nematode genera. In sheep, a highly effective reduction in the total number of larvae was observed for all treatments, with null means for treatments 100, 50 and 30%. Such results indicate that Carapa guianensis (Andiroba) seed oil has in vitro activity against larvae from gastrointestinal nematodes of goats and sheep.

anthelmintic; medicinal plants; ruminants


Sociedade Brasileira de Plantas Medicinais Sociedade Brasileira de Plantas Medicinais, Revista Brasileira de Plantas Medicinais, Universidade Estadual de Maringá, Departamento de Farmácia, Bloco T22, Avenida Colombo, 5790, 87020-900 - Maringá - PR, Tel: +55-44-3011-4627 - Botucatu - SP - Brazil
E-mail: revista@sbpmed.org.br