The emergence of resistant parasite populations has led to the study of pharmaceutical drugs, which represent an alternative control. This study aimed to evaluate the antibacterial activity and to perform the phytochemical analysis of the ethanol extract from two species belonging to the semi-arid region of Paraíba State, Brazil: Solanum paniculatum Lam. and Operculina hamiltonii (G. Don) D. F. Austin & Staples. Such species have been largely used by the rural population against ovine gastrointestinal helminthes. Phytochemical prospection was obtained from ethanol extracts for analysis of chemical compounds present in both species. Extract analyses indicated the presence of condensed tannins, flavonols, flavanones, and alkaloids in both species. The antibacterial activity was initially determined by the cavity method. The species S. paniculatum had activity against Staphylococcus aureus (ATCC 12692), Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 15442); however, O. hamintonii did not present activity against the tested bacterial strains.
Solanum paniculatum; Operculina hamiltonii; ethanol extracts; antibacterial activity
